Ibrance and Cardiac murmur - a phase IV clinical study of FDA data

Summary:

Cardiac murmur is reported as a side effect among people who take Ibrance (palbociclib), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Letrozole, and have Breast cancer female.

The phase IV clinical study analyzes which people have Cardiac murmur when taking Ibrance. It is created by eHealthMe based on reports of 104,340 people who have side effects when taking Ibrance from the FDA, and is updated regularly.

What is Ibrance?

Ibrance has active ingredients of palbociclib. eHealthMe is studying from 104,434 Ibrance users. Check the latest studies of Ibrance.

What is Cardiac murmur?

Cardiac murmur (an heart sound in valve abnormality) is found to be associated with 1,164 drugs and 1,153 conditions by eHealthMe. Check the latest studies of Cardiac murmur.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

104,340 people reported to have side effects when taking Ibrance.
Among them, 27 people (0.03%) have Cardiac murmur.

Among these 27 people:

How long have people been on Ibrance when they have Cardiac murmur? *

What is the gender of people who have Cardiac murmur when taking Ibrance? *

female: 100 %
male: 0.0 %

What is the age of people who have Cardiac murmur when taking Ibrance? *

What are other drugs people take besides Ibrance? *

What are other side effects people have besides Cardiac murmur? *

Fatigue (feeling of tiredness): 14 people, 51.85%
White Blood Cell Count Decreased: 12 people, 44.44%
Haemorrhage (bleeding): 8 people, 29.63%
Weight Decreased: 7 people, 25.93%
Neoplasm Progression (growth of tumour): 7 people, 25.93%
Red Blood Cell Count Decreased: 6 people, 22.22%
Dizziness Postural: 6 people, 22.22%
Anaemia (lack of blood): 5 people, 18.52%
Muscle Aches (muscle pain): 5 people, 18.52%
Hypotension (abnormally low blood pressure): 5 people, 18.52%

What are the existing conditions these people have? *

Breast Cancer Female: 11 people, 40.74%
High Blood Pressure: 8 people, 29.63%
Breast Cancer Stage Iv: 7 people, 25.93%
Breast Cancer Metastatic: 7 people, 25.93%
Breast Cancer: 6 people, 22.22%
Bone Loss: 3 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Ibrance and have Cardiac murmur?

- Check whether Cardiac murmur is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibrance:

Ibrance (104,434 reports)

Cardiac murmur treatments and more:

Cardiac murmur (14,521 reports)

Browse all side effects of Ibrance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiac murmur:

Cardiac murmur (1,164 drugs)

Browse all the conditions that are associated with Cardiac murmur:

Cardiac murmur (1,153 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on palbociclib (the active ingredients of Ibrance) and Ibrance (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.