Enhertu and Enterocolitis - a phase IV clinical study of FDA data

Summary:

Enterocolitis is reported as a side effect among people who take Enhertu (fam-trastuzumab deruxtecan-nxki), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Candesartan Cilexetil, and have Constipation.

The phase IV clinical study analyzes which people have Enterocolitis when taking Enhertu. It is created by eHealthMe based on reports of 5,111 people who have side effects when taking Enhertu from the FDA, and is updated regularly.

What is Enhertu?

Enhertu has active ingredients of fam-trastuzumab deruxtecan-nxki. eHealthMe is studying from 5,113 Enhertu users. Check the latest studies of Enhertu.

What is Enterocolitis?

Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon) is found to be associated with 659 drugs and 732 conditions by eHealthMe. Check the latest studies of Enterocolitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

5,111 people reported to have side effects when taking Enhertu.
Among them, 12 people (0.23%) have Enterocolitis.

Among these 12 people:

How long have people been on Enhertu when they have Enterocolitis? *

What is the gender of people who have Enterocolitis when taking Enhertu? *

female: 83.33 %
male: 16.67 %

What is the age of people who have Enterocolitis when taking Enhertu? *

What are other drugs people take besides Enhertu? *

Zoledronic Acid: 4 people, 33.33%
Magnesium Oxide: 4 people, 33.33%
Hydromorphone Hydrochloride: 4 people, 33.33%
Candesartan Cilexetil: 4 people, 33.33%
Octreotide Acetate: 2 people, 16.67%
Lansoprazole: 2 people, 16.67%

What are other side effects people have besides Enterocolitis? *

Anaemia (lack of blood): 8 people, 66.67%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 5 people, 41.67%
Nausea (feeling of having an urge to vomit): 5 people, 41.67%
Fever: 5 people, 41.67%
Septic Shock (shock due to blood infection): 4 people, 33.33%
Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 4 people, 33.33%
Cellulitis (infection under the skin): 4 people, 33.33%
Dental Caries: 4 people, 33.33%
Diarrhea: 4 people, 33.33%
Disease Progression: 4 people, 33.33%

What are the existing conditions these people have? *

Pain: 5 people, 41.67%
Nausea (feeling of having an urge to vomit): 5 people, 41.67%
Metastases To Uterus (cancer spreads to uterus): 5 people, 41.67%
Metastases To Peritoneum (cancer spreads to peritoneum): 5 people, 41.67%
Metastases To Lymph Nodes (cancer spreads to lymph node): 5 people, 41.67%
Metastases To Bone (cancer spreads to bone): 5 people, 41.67%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 5 people, 41.67%
High Blood Pressure: 5 people, 41.67%
Hepatic Function Abnormal: 5 people, 41.67%
Constipation: 5 people, 41.67%

* Approximation only. Some reports may have incomplete information.

Do you take Enhertu and have Enterocolitis?

- Check whether Enterocolitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Enhertu:

Enhertu (5,113 reports)

Enterocolitis treatments and more:

Enterocolitis (7,684 reports)

How severe was Enterocolitis and when was it recovered:

Enterocolitis in Enhertu

Expand to all the drugs that have ingredients of fam-trastuzumab deruxtecan-nxki:

Enterocolitis and drugs with ingredients of fam-trastuzumab deruxtecan-nxki

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Enhertu:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Enterocolitis:

Enterocolitis (660 drugs)

Browse all the conditions that are associated with Enterocolitis:

Enterocolitis (732 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fam-trastuzumab deruxtecan-nxki (the active ingredients of Enhertu) and Enhertu (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.