Epa and Fever - a phase IV clinical study of FDA data

Summary:

Fever is reported as a side effect among people who take Epa (epa (eicosapentaenoic acid)), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Rabeprazole, and have Insomnia.

The phase IV clinical study analyzes which people have Fever when taking Epa. It is created by eHealthMe based on reports of 591 people who have side effects when taking Epa from the FDA, and is updated regularly.

What is Epa?

Epa has active ingredients of epa (eicosapentaenoic acid). It is often used in high blood cholesterol. eHealthMe is studying from 623 Epa users. Check the latest studies of Epa.

What is Fever?

Fever is found to be associated with 3,491 drugs and 6,184 conditions by eHealthMe. Check the latest studies of Fever.

On May, 01, 2026

591 people reported to have side effects when taking Epa.
Among them, 31 people (5.25%) have Fever.

Among these 31 people:

How long have people been on Epa when they have Fever? *

What is the gender of people who have Fever when taking Epa? *

female: 59.26 %
male: 40.74 %

What is the age of people who have Fever when taking Epa? *

What are other drugs people take besides Epa? *

What are other side effects people have besides Fever? *

Fatigue (feeling of tiredness): 13 people, 41.94%
Weakness: 13 people, 41.94%
Malaise (a feeling of general discomfort or uneasiness): 12 people, 38.71%
Pain In Extremity: 12 people, 38.71%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 12 people, 38.71%
Nausea And Vomiting: 10 people, 32.26%
Neuropathy Peripheral (surface nerve damage): 8 people, 25.81%
Drug Ineffective: 8 people, 25.81%
Drug Hypersensitivity: 8 people, 25.81%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 25.81%

What are the existing conditions these people have? *

Insomnia (sleeplessness): 7 people, 22.58%
High Blood Pressure: 6 people, 19.35%
Bipolar Disorder (mood disorder): 5 people, 16.13%
Stress And Anxiety: 5 people, 16.13%
Irritability: 4 people, 12.90%
Constipation: 4 people, 12.90%
Type 2 Diabetes: 4 people, 12.90%
Abulia (lack of will or initiative): 4 people, 12.90%
Stupor (lack of critical cognitive function and level of consciousness): 4 people, 12.90%
Emotional Disorder Of Childhood: 3 people, 9.68%

* Approximation only. Some reports may have incomplete information.

Do you take Epa and have Fever?

- Check whether Fever is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Epa:

Epa (623 reports)

Fever treatments and more:

Fever (498,666 reports)

Browse all side effects of Epa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fever:

Fever (3,491 drugs)

Browse all the conditions that are associated with Fever:

Fever (6,184 conditions)

Related publications that referenced our studies

Schiller D, Maieron A, Sch?fl R, Donnerer J, "Drug fever due to a single dose of pantoprazole", Pharmacology, 2015 Jan .
Schiller D, Maieron A, Sch?fl R, Donnerer J, "Drug fever due to a single dose of pantoprazole", Pharmacology, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on epa (eicosapentaenoic acid) (the active ingredients of Epa) and Epa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.