Epinephrine and Facial paralysis - a phase IV clinical study of FDA data

Summary:

Facial paralysis is reported as a side effect among people who take Epinephrine (epinephrine), especially for people who are female, 50-59 old, also take Lidocaine, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Facial paralysis when taking Epinephrine. It is created by eHealthMe based on reports of 21,223 people who have side effects when taking Epinephrine from the FDA, and is updated regularly.

What is Epinephrine?

Epinephrine has active ingredients of epinephrine. It is often used in asthma. eHealthMe is studying from 21,290 Epinephrine users. Check the latest studies of Epinephrine.

What is Facial paralysis?

Facial paralysis (loss of function of face muscle) is found to be associated with 661 drugs and 1,151 conditions by eHealthMe. Check the latest studies of Facial paralysis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

21,223 people reported to have side effects when taking Epinephrine.
Among them, 12 people (0.06%) have Facial paralysis.

Could Epinephrine cause Facial paralysis?

Among these 12 people:

What is the gender of people who have Facial paralysis when taking Epinephrine? *

female: 91.67 %
male: 8.33 %

What is the age of people who have Facial paralysis when taking Epinephrine? *

What are other drugs people take besides Epinephrine? *

Lidocaine: 7 people, 58.33%
Acetaminophen: 5 people, 41.67%
Sodium Chloride: 5 people, 41.67%
Albuterol Sulfate: 5 people, 41.67%
Heparin: 4 people, 33.33%
Methocarbamol: 4 people, 33.33%
Clonidine: 4 people, 33.33%
Metformin: 4 people, 33.33%
Memantine: 4 people, 33.33%
Meclizine Hydrochloride: 4 people, 33.33%

What are other side effects people have besides Facial paralysis? *

Fatigue (feeling of tiredness): 6 people, 50.00%
Headache (pain in head): 6 people, 50.00%
Swallowing Difficulty: 5 people, 41.67%
Oedema (fluid collection in tissue): 5 people, 41.67%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 5 people, 41.67%
Migraine (headache): 5 people, 41.67%
Speech Impairment (Adult) (inability to speak (adult)): 5 people, 41.67%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 41.67%
Cough: 5 people, 41.67%
Infusion Site Erythema (reddening of the skin at infusion site): 5 people, 41.67%

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 6 people, 50.00%
Local Anaesthesia: 3 people, 25.00%
Infiltration Anaesthesia: 1 person, 8.33%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 1 person, 8.33%
Hypersensitivity: 1 person, 8.33%
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 1 person, 8.33%
Anaesthesia: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Epinephrine and have Facial paralysis?

- Check whether Facial paralysis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Epinephrine:

Epinephrine (21,290 reports)

Browse all side effects of Epinephrine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Facial paralysis:

Facial paralysis (661 drugs)

Browse all the conditions that are associated with Facial paralysis:

Facial paralysis (1,151 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on epinephrine (the active ingredients of Epinephrine) and Epinephrine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.