Epival and Swallowing difficulty - a phase IV clinical study of FDA data

Summary:

Swallowing difficulty is reported as a side effect among people who take Epival (divalproex sodium), especially for people who are female, 40-49 old, also take Clozaril, and have Schizophrenia.

The phase IV clinical study analyzes which people have Swallowing difficulty when taking Epival. It is created by eHealthMe based on reports of 968 people who have side effects when taking Epival from the FDA, and is updated regularly.

What is Epival?

Epival has active ingredients of divalproex sodium. It is often used in epilepsy. eHealthMe is studying from 1,088 Epival users. Check the latest studies of Epival.

What is Swallowing difficulty?

Swallowing difficulty is found to be associated with 2,403 drugs and 3,350 conditions by eHealthMe. Check the latest studies of Swallowing difficulty.

On May, 04, 2026

968 people reported to have side effects when taking Epival.
Among them, 14 people (1.45%) have Swallowing difficulty.

Could Epival cause Swallowing difficulty?

Among these 14 people:

What is the gender of people who have Swallowing difficulty when taking Epival? *

female: 61.54 %
male: 38.46 %

What is the age of people who have Swallowing difficulty when taking Epival? *

What are other drugs people take besides Epival? *

What are other side effects people have besides Swallowing difficulty? *

Urinary Incontinence (inability to control the flow of urine and involuntary urination): 3 people, 21.43%
Headache (pain in head): 3 people, 21.43%
Weight Decreased: 3 people, 21.43%
Gait Disturbance: 3 people, 21.43%
Body Temperature Increased: 3 people, 21.43%
Productive Cough: 2 people, 14.29%
Respiratory Tract Infection Viral: 2 people, 14.29%
General Physical Health Deterioration (weak health status): 2 people, 14.29%
Hypotension (abnormally low blood pressure): 2 people, 14.29%
Drooling (drop saliva uncontrollably from the mouth): 2 people, 14.29%

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 5 people, 35.71%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 21.43%
Schizoaffective Disorder Bipolar Type (mental illness featuring schizophrenia and a mood disorder with mania): 1 person, 7.14%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 7.14%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 7.14%
Pain: 1 person, 7.14%
Mental Retardation (problems with learning and developing): 1 person, 7.14%
Insomnia (sleeplessness): 1 person, 7.14%
Breast Cancer Stage Iv: 1 person, 7.14%
Abnormal Behavior: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Epival and have Swallowing difficulty?

- Check whether Swallowing difficulty is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Epival:

Epival (1,088 reports)

Browse all side effects of Epival:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Swallowing difficulty:

Swallowing difficulty (2,403 drugs)

Browse all the conditions that are associated with Swallowing difficulty:

Swallowing difficulty (3,350 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on divalproex sodium (the active ingredients of Epival) and Epival (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.