Eplerenone and Acne - a phase IV clinical study of FDA data

Summary:

Acne is reported as a side effect among people who take Eplerenone (eplerenone), especially for people who are male, 60+ old, also take Entresto, and have Blood creatinine increased.

The phase IV clinical study analyzes which people have Acne when taking Eplerenone. It is created by eHealthMe based on reports of 9,846 people who have side effects when taking Eplerenone from the FDA, and is updated regularly.

What is Eplerenone?

Eplerenone has active ingredients of eplerenone. It is often used in high blood pressure. eHealthMe is studying from 9,979 Eplerenone users. Check the latest studies of Eplerenone.

What is Acne?

Acne (skin problems that cause pimples) is found to be associated with 1,313 drugs and 2,357 conditions by eHealthMe. Check the latest studies of Acne.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

9,846 people reported to have side effects when taking Eplerenone.
Among them, 20 people (0.2%) have Acne.

Among these 20 people:

What is the gender of people who have Acne when taking Eplerenone? *

female: 5.88 %
male: 94.12 %

What is the age of people who have Acne when taking Eplerenone? *

What are other drugs people take besides Eplerenone? *

Entresto: 11 people, 55.00%
Pantoprazole: 8 people, 40.00%
Potassium Chloride: 5 people, 25.00%
Amlodipine: 5 people, 25.00%
Metformin Hydrochloride: 4 people, 20.00%
Minocycline: 4 people, 20.00%
Isturisa: 3 people, 15.00%
Jardiance: 3 people, 15.00%
Xarelto: 3 people, 15.00%
Lisinopril: 3 people, 15.00%

What are other side effects people have besides Acne? *

Fatigue (feeling of tiredness): 11 people, 55.00%
Blood Creatinine Increased: 10 people, 50.00%
Nausea (feeling of having an urge to vomit): 9 people, 45.00%
Thrombocytopenia (decrease of platelets in blood): 8 people, 40.00%
Infection: 6 people, 30.00%
Rashes (redness): 6 people, 30.00%
Weight Decreased: 3 people, 15.00%
Pain: 3 people, 15.00%
Hypokalemia (low potassium): 3 people, 15.00%
Hypersensitivity: 3 people, 15.00%

What are the existing conditions these people have? *

Viral Cardiomyopathy (weakness in the muscle of the heart due to viral infection): 8 people, 40.00%
Idiopathic Thrombocytopenic Purpura (Itp) (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 8 people, 40.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 40.00%
Blood Creatinine Increased: 8 people, 40.00%
Cardiac Failure: 5 people, 25.00%
Diabetes: 4 people, 20.00%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 3 people, 15.00%
Hyperaldosteronism: 3 people, 15.00%
Cushing's Syndrome (obesity, a rounded face, increased fat): 3 people, 15.00%
Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Eplerenone and have Acne?

- Check whether Acne is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Eplerenone:

Eplerenone (9,979 reports)

Acne treatments and more:

Acne (179,011 reports)

Browse all side effects of Eplerenone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acne:

Acne (1,313 drugs)

Browse all the conditions that are associated with Acne:

Acne (2,357 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on eplerenone (the active ingredients of Eplerenone) and Eplerenone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.