Eplerenone and Shock - a phase IV clinical study of FDA data

Summary:

Shock is reported as a side effect among people who take Eplerenone (eplerenone), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Olmesartan Medoxomil, and have Cardiac failure.

The phase IV clinical study analyzes which people have Shock when taking Eplerenone. It is created by eHealthMe based on reports of 9,846 people who have side effects when taking Eplerenone from the FDA, and is updated regularly.

What is Eplerenone?

Eplerenone has active ingredients of eplerenone. It is often used in high blood pressure. eHealthMe is studying from 9,979 Eplerenone users. Check the latest studies of Eplerenone.

What is Shock?

Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin) is found to be associated with 1,213 drugs and 1,755 conditions by eHealthMe. Check the latest studies of Shock.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

9,846 people reported to have side effects when taking Eplerenone.
Among them, 21 people (0.21%) have Shock.

Among these 21 people:

How long have people been on Eplerenone when they have Shock? *

What is the gender of people who have Shock when taking Eplerenone? *

female: 15 %
male: 85 %

What is the age of people who have Shock when taking Eplerenone? *

What are other drugs people take besides Eplerenone? *

What are other side effects people have besides Shock? *

Hyperkalemia (damage to or disease of the kidney): 9 people, 42.86%
Bradycardia (abnormally slow heart action): 5 people, 23.81%
Dyspnea (difficult or laboured breathing): 5 people, 23.81%
Hypotension (abnormally low blood pressure): 5 people, 23.81%
Sick Sinus Syndrome (a collection of heart rhythm disorders): 5 people, 23.81%
Blood Creatinine Increased: 4 people, 19.05%
Chest Pain: 4 people, 19.05%
Concussion (short loss of normal brain function in response to a head injury): 4 people, 19.05%
Delusion (a false belief or opinion): 4 people, 19.05%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 19.05%

What are the existing conditions these people have? *

Cardiac Failure: 5 people, 23.81%
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 4 people, 19.05%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 19.05%
Hyperthyroidism (over activity of the thyroid gland): 4 people, 19.05%
Otitis Media (inflammation of the middle ear): 3 people, 14.29%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 9.52%
Type 2 Diabetes: 1 person, 4.76%
Suicide Attempt: 1 person, 4.76%
Sedation: 1 person, 4.76%
Nasopharyngitis (inflammation of the nasopharynx): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Eplerenone and have Shock?

- Check whether Shock is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Eplerenone:

Eplerenone (9,979 reports)

Shock treatments and more:

Shock (28,534 reports)

Browse all side effects of Eplerenone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Shock:

Shock (1,213 drugs)

Browse all the conditions that are associated with Shock:

Shock (1,755 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on eplerenone (the active ingredients of Eplerenone) and Eplerenone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.