Esbriet and Fibromyalgia - a phase IV clinical study of FDA data

Summary:

Fibromyalgia is reported as a side effect among people who take Esbriet (pirfenidone), especially for people who are female, 60+ old, also take Vitamin D3, and have Idiopathic pulmonary fibrosis.

The phase IV clinical study analyzes which people have Fibromyalgia when taking Esbriet. It is created by eHealthMe based on reports of 39,843 people who have side effects when taking Esbriet from the FDA, and is updated regularly.

What is Esbriet?

Esbriet has active ingredients of pirfenidone. eHealthMe is studying from 39,858 Esbriet users. Check the latest studies of Esbriet.

What is Fibromyalgia?

Fibromyalgia (a long-term condition which causes pain all over the body) is found to be associated with 1,337 drugs and 1,832 conditions by eHealthMe. Check the latest studies of Fibromyalgia.

On Jul, 17, 2026

39,843 people reported to have side effects when taking Esbriet.
Among them, 24 people (0.06%) have Fibromyalgia.

Among these 24 people:

What is the gender of people who have Fibromyalgia when taking Esbriet? *

female: 91.3 %
male: 8.7 %

What is the age of people who have Fibromyalgia when taking Esbriet? *

What are other drugs people take besides Esbriet? *

What are other side effects people have besides Fibromyalgia? *

Diarrhea: 9 people, 37.50%
Fatigue (feeling of tiredness): 8 people, 33.33%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 7 people, 29.17%
Dyspnea (difficult or laboured breathing): 7 people, 29.17%
Pain: 6 people, 25.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 25.00%
Urinary Tract Infection: 6 people, 25.00%
Nausea (feeling of having an urge to vomit): 6 people, 25.00%
Chest Pain: 6 people, 25.00%
Indigestion: 5 people, 20.83%

What are the existing conditions these people have? *

Idiopathic Pulmonary Fibrosis (chronic lung disease): 18 people, 75.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 12.50%
Drowsiness: 3 people, 12.50%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 12.50%
Colon Cancer: 2 people, 8.33%
Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 8.33%
Pain: 2 people, 8.33%
Interstitial Lung Disease: 1 person, 4.17%
Muscle Spasms (muscle contraction): 1 person, 4.17%
Stress And Anxiety: 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Esbriet and have Fibromyalgia?

- Check whether Fibromyalgia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Esbriet:

Esbriet (39,858 reports)

Fibromyalgia treatments and more:

Fibromyalgia (92,987 reports)

Browse all side effects of Esbriet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fibromyalgia:

Fibromyalgia (1,337 drugs)

Browse all the conditions that are associated with Fibromyalgia:

Fibromyalgia (1,832 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pirfenidone (the active ingredients of Esbriet) and Esbriet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.