Escitalopram and Hyperthyroidism - a phase IV clinical study of FDA data

Summary:

Hyperthyroidism is reported as a side effect among people who take Escitalopram (escitalopram oxalate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Metformin, and have High blood pressure.

The phase IV clinical study analyzes which people have Hyperthyroidism when taking Escitalopram. It is created by eHealthMe based on reports of 75,134 people who have side effects when taking Escitalopram from the FDA, and is updated regularly.

What is Escitalopram?

Escitalopram has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 78,080 Escitalopram users. Check the latest studies of Escitalopram.

What is Hyperthyroidism?

Hyperthyroidism (over activity of the thyroid gland) is found to be associated with 975 drugs and 1,437 conditions by eHealthMe. Check the latest studies of Hyperthyroidism.

On Apr, 27, 2026

75,134 people reported to have side effects when taking Escitalopram.
Among them, 69 people (0.09%) have Hyperthyroidism.

Could Escitalopram cause Hyperthyroidism?

Among these 69 people:

How long have people been on Escitalopram when they have Hyperthyroidism? *

What is the gender of people who have Hyperthyroidism when taking Escitalopram? *

female: 69.12 %
male: 30.88 %

What is the age of people who have Hyperthyroidism when taking Escitalopram? *

What are other drugs people take besides Escitalopram? *

What are other side effects people have besides Hyperthyroidism? *

Fatigue (feeling of tiredness): 16 people, 23.19%
Pain: 9 people, 13.04%
Diarrhea: 9 people, 13.04%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 9 people, 13.04%
Urinary Tract Infection: 8 people, 11.59%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 8 people, 11.59%
Thyroid Diseases: 8 people, 11.59%
Weight Decreased: 7 people, 10.14%
Joint Pain: 7 people, 10.14%
Weakness: 7 people, 10.14%

What are the existing conditions these people have? *

High Blood Pressure: 12 people, 17.39%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 13.04%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 10.14%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 7.25%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 4 people, 5.80%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 5.80%
Burnout Syndrome (problems related to life-management difficulty, but not considered a ""disorder): 4 people, 5.80%
Birth Control: 4 people, 5.80%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 4.35%
Cardiac Failure: 3 people, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Escitalopram and have Hyperthyroidism?

- Check whether Hyperthyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Escitalopram:

Escitalopram (78,080 reports)

Hyperthyroidism treatments and more:

Hyperthyroidism (26,832 reports)

Browse all side effects of Escitalopram:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperthyroidism:

Hyperthyroidism (975 drugs)

Browse all the conditions that are associated with Hyperthyroidism:

Hyperthyroidism (1,437 conditions)

Related publications that referenced our studies

O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .
O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on escitalopram oxalate (the active ingredients of Escitalopram) and Escitalopram (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.