Escitalopram and Systolic dysfunction - a phase IV clinical study of FDA data

Summary:

Systolic dysfunction is reported as a side effect among people who take Escitalopram (escitalopram oxalate), especially for people who are female, 40-49 old, also take Ondansetron, and have Pain.

The phase IV clinical study analyzes which people have Systolic dysfunction when taking Escitalopram. It is created by eHealthMe based on reports of 75,134 people who have side effects when taking Escitalopram from the FDA, and is updated regularly.

What is Escitalopram?

Escitalopram has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 78,081 Escitalopram users. Check the latest studies of Escitalopram.

What is Systolic dysfunction?

Systolic dysfunction (impaired ventricular contraction) is found to be associated with 200 drugs and 220 conditions by eHealthMe. Check the latest studies of Systolic dysfunction.

On Aug, 11, 2026

75,134 people reported to have side effects when taking Escitalopram.
Among them, 11 people (0.01%) have Systolic dysfunction.

Could Escitalopram cause Systolic dysfunction?

Among these 11 people:

What is the gender of people who have Systolic dysfunction when taking Escitalopram? *

female: 80 %
male: 20 %

What is the age of people who have Systolic dysfunction when taking Escitalopram? *

What are other drugs people take besides Escitalopram? *

What are other side effects people have besides Systolic dysfunction? *

Right Ventricular Failure (right half of the heart fails to work): 7 people, 63.64%
Abdominal Pain: 6 people, 54.55%
Endometritis (inflammation of the endometrium): 6 people, 54.55%
Hepatic Function Abnormal: 6 people, 54.55%
Escherichia Infection (bacterial infection by escherichia coli): 6 people, 54.55%
Right Atrial Dilatation (enlargement of the right atrium chamber of heart): 6 people, 54.55%
Blood Bilirubin Increased: 6 people, 54.55%
High Blood Pressure: 6 people, 54.55%
Total Bile Acids Increased: 6 people, 54.55%
Tricuspid Valve Incompetence (inefficient heart valve): 6 people, 54.55%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 27.27%
Pain: 3 people, 27.27%
Total Bile Acids Increased: 2 people, 18.18%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Escitalopram and have Systolic dysfunction?

- Check whether Systolic dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Escitalopram:

Escitalopram (78,081 reports)

Browse all side effects of Escitalopram:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Systolic dysfunction:

Systolic dysfunction (200 drugs)

Browse all the conditions that are associated with Systolic dysfunction:

Systolic dysfunction (220 conditions)

Related publications that referenced our studies

O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on escitalopram oxalate (the active ingredients of Escitalopram) and Escitalopram (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.