Estring and Thinking abnormal - a phase IV clinical study of FDA data

Summary:

Thinking abnormal is reported as a side effect among people who take Estring (estradiol), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Gabapentin, and have Atrophic vulvovaginitis.

The phase IV clinical study analyzes which people have Thinking abnormal when taking Estring. It is created by eHealthMe based on reports of 5,418 people who have side effects when taking Estring from the FDA, and is updated regularly.

What is Estring?

Estring has active ingredients of estradiol. eHealthMe is studying from 5,474 Estring users. Check the latest studies of Estring.

What is Thinking abnormal?

Thinking abnormal is found to be associated with 1,130 drugs and 1,178 conditions by eHealthMe. Check the latest studies of Thinking abnormal.

On Jan, 21, 2026

5,418 people reported to have side effects when taking Estring.
Among them, 14 people (0.26%) have Thinking abnormal.

Among these 14 people:

How long have people been on Estring when they have Thinking abnormal? *

What is the gender of people who have Thinking abnormal when taking Estring? *

female: 100 %
male: 0.0 %

What is the age of people who have Thinking abnormal when taking Estring? *

What are other drugs people take besides Estring? *

What are other side effects people have besides Thinking abnormal? *

Fatigue (feeling of tiredness): 5 people, 35.71%
Optic Nerve Disorder (disease of optic nerve): 3 people, 21.43%
Mobility Decreased (ability to move is reduced): 3 people, 21.43%
Dysgraphia (impaired ability to learn to write): 3 people, 21.43%
Post Procedural Complication: 3 people, 21.43%
Weakness: 3 people, 21.43%
Tremor (trembling or shaking movements in one or more parts of your body): 3 people, 21.43%
Decreased Immune Responsiveness: 3 people, 21.43%
Chills (felling of cold): 3 people, 21.43%
Blindness Unilateral: 3 people, 21.43%

What are the existing conditions these people have? *

Atrophic Vulvovaginitis (inflammation of the vulva): 4 people, 28.57%
Insomnia (sleeplessness): 3 people, 21.43%
Stress And Anxiety: 3 people, 21.43%
Diabetes: 3 people, 21.43%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 3 people, 21.43%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 21.43%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 21.43%
High Blood Cholesterol: 3 people, 21.43%
High Blood Pressure: 3 people, 21.43%
Immunodeficiency: 3 people, 21.43%

* Approximation only. Some reports may have incomplete information.

Do you take Estring and have Thinking abnormal?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Estring:

Estring (5,474 reports)

Browse all side effects of Estring:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thinking abnormal:

Thinking abnormal (1,130 drugs)

Browse all the conditions that are associated with Thinking abnormal:

Thinking abnormal (1,178 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on estradiol (the active ingredients of Estring) and Estring (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.