Etodolac and Rectal haemorrhage - a phase IV clinical study of FDA data

Summary:

Rectal haemorrhage is reported as a side effect among people who take Etodolac (etodolac), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Lyrica, and have Hypercalcaemia.

The phase IV clinical study analyzes which people have Rectal haemorrhage when taking Etodolac. It is created by eHealthMe based on reports of 8,707 people who have side effects when taking Etodolac from the FDA, and is updated regularly.

What is Etodolac?

Etodolac has active ingredients of etodolac. It is often used in arthritis. eHealthMe is studying from 9,157 Etodolac users. Check the latest studies of Etodolac.

What is Rectal haemorrhage?

Rectal haemorrhage (bleeding from anus) is found to be associated with 1,730 drugs and 1,597 conditions by eHealthMe. Check the latest studies of Rectal haemorrhage.

On Jul, 08, 2026

8,707 people reported to have side effects when taking Etodolac.
Among them, 62 people (0.71%) have Rectal haemorrhage.

Could Etodolac cause Rectal haemorrhage?

Among these 62 people:

How long have people been on Etodolac when they have Rectal haemorrhage? *

What is the gender of people who have Rectal haemorrhage when taking Etodolac? *

female: 54.84 %
male: 45.16 %

What is the age of people who have Rectal haemorrhage when taking Etodolac? *

What are other drugs people take besides Etodolac? *

Lyrica: 23 people, 37.10%
Gabapentin: 21 people, 33.87%
Levaquin: 20 people, 32.26%
Lexapro: 20 people, 32.26%
Lipitor: 20 people, 32.26%
Avelox: 20 people, 32.26%
Mobic: 19 people, 30.65%
Wellbutrin Xl: 19 people, 30.65%
Citalopram Hydrobromide: 19 people, 30.65%
Folic Acid: 19 people, 30.65%

What are other side effects people have besides Rectal haemorrhage? *

Haemorrhoids (a swollen vein or group of veins in the region of the anus): 22 people, 35.48%
Back Pain: 21 people, 33.87%
Anaemia (lack of blood): 20 people, 32.26%
Weakness: 20 people, 32.26%
Joint Pain: 20 people, 32.26%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 20 people, 32.26%
Anorectal Abscess: 19 people, 30.65%
Haemangioma (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs): 19 people, 30.65%
Herniated Nucleus Pulposus (Slipped Disk): 19 people, 30.65%
Hypoaesthesia (reduced sense of touch or sensation): 19 people, 30.65%

What are the existing conditions these people have? *

Breast Cancer: 16 people, 25.81%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 16 people, 25.81%
Breast Cancer Metastatic: 15 people, 24.19%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 12.90%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 6.45%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 6.45%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 4.84%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 4.84%
Fatigue (feeling of tiredness): 3 people, 4.84%
Gait Disturbance: 3 people, 4.84%

* Approximation only. Some reports may have incomplete information.

Do you take Etodolac and have Rectal haemorrhage?

- Check whether Rectal haemorrhage is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Etodolac:

Etodolac (9,157 reports)

Browse all side effects of Etodolac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rectal haemorrhage:

Rectal haemorrhage (1,730 drugs)

Browse all the conditions that are associated with Rectal haemorrhage:

Rectal haemorrhage (1,597 conditions)

Related publications that referenced our studies

Liao KF, Cheng KC, Lin CL, Lai SW, "Etodolac and the risk of acute pancreatitis", BioMedicine, 2017 Jan .
Liao KF, Cheng KC, Lin CL, Lai SW, "Etodolac and the risk of acute pancreatitis", BioMedicine, 2017 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on etodolac (the active ingredients of Etodolac) and Etodolac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.