Evoxac and Aspartate aminotransferase increased - a phase IV clinical study of FDA data

Summary:

Aspartate aminotransferase increased is reported as a side effect among people who take Evoxac (cevimeline hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Aspirin, and have Anaemia.

The phase IV clinical study analyzes which people have Aspartate aminotransferase increased when taking Evoxac. It is created by eHealthMe based on reports of 1,960 people who have side effects when taking Evoxac from the FDA, and is updated regularly.

What is Evoxac?

Evoxac has active ingredients of cevimeline hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 2,028 Evoxac users. Check the latest studies of Evoxac.

What is Aspartate aminotransferase increased?

Aspartate aminotransferase increased is found to be associated with 2,089 drugs and 3,379 conditions by eHealthMe. Check the latest studies of Aspartate aminotransferase increased.

On Jun, 17, 2026

1,960 people reported to have side effects when taking Evoxac.
Among them, 15 people (0.77%) have Aspartate aminotransferase increased.

Could Evoxac cause Aspartate aminotransferase increased?

Among these 15 people:

How long have people been on Evoxac when they have Aspartate aminotransferase increased? *

What is the gender of people who have Aspartate aminotransferase increased when taking Evoxac? *

female: 86.67 %
male: 13.33 %

What is the age of people who have Aspartate aminotransferase increased when taking Evoxac? *

What are other drugs people take besides Evoxac? *

What are other side effects people have besides Aspartate aminotransferase increased? *

Alanine Aminotransferase Increased: 15 people, 100.00%
Malaise (a feeling of general discomfort or uneasiness): 7 people, 46.67%
Blood Alkaline Phosphatase Increased: 5 people, 33.33%
Gamma-Glutamyltransferase Increased: 4 people, 26.67%
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 4 people, 26.67%
Nausea And Vomiting: 4 people, 26.67%
Nausea (feeling of having an urge to vomit): 4 people, 26.67%
Nasopharyngitis (inflammation of the nasopharynx): 3 people, 20.00%
Fatigue (feeling of tiredness): 3 people, 20.00%
Cholecystitis Acute (rapid infection of gallbladder): 3 people, 20.00%

What are the existing conditions these people have? *

Neuropathy Peripheral (surface nerve damage): 2 people, 13.33%
Hiv Infection: 2 people, 13.33%
High Blood Pressure: 2 people, 13.33%
High Blood Cholesterol: 2 people, 13.33%
Diabetes: 2 people, 13.33%
Cerebral Infarction (less blood supply to brain resulting tissue damage): 2 people, 13.33%
Anaemia (lack of blood): 2 people, 13.33%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 6.67%
Pneumonia Staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus): 1 person, 6.67%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Evoxac and have Aspartate aminotransferase increased?

- Check whether Aspartate aminotransferase increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Evoxac:

Evoxac (2,028 reports)

Browse all side effects of Evoxac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aspartate aminotransferase increased:

Aspartate aminotransferase increased (2,089 drugs)

Browse all the conditions that are associated with Aspartate aminotransferase increased:

Aspartate aminotransferase increased (3,379 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cevimeline hydrochloride (the active ingredients of Evoxac) and Evoxac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.