Excedrin and Ear buzzing - a phase IV clinical study of FDA data

Summary:

Ear buzzing is reported as a side effect among people who take Excedrin (acetaminophen; aspirin; caffeine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tylenol, and have Hot flush.

The phase IV clinical study analyzes which people have Ear buzzing when taking Excedrin. It is created by eHealthMe based on reports of 21,620 people who have side effects when taking Excedrin from the FDA, and is updated regularly.

What is Excedrin?

Excedrin has active ingredients of acetaminophen; aspirin; caffeine. It is often used in headache. eHealthMe is studying from 22,739 Excedrin users. Check the latest studies of Excedrin.

What is Ear buzzing?

Ear buzzing is found to be associated with 2,356 drugs and 3,091 conditions by eHealthMe. Check the latest studies of Ear buzzing.

On Dec, 15, 2025

21,620 people reported to have side effects when taking Excedrin.
Among them, 136 people (0.63%) have Ear buzzing.

Among these 136 people:

* Approximation only. Some reports may have incomplete information.

Do you take Excedrin and have Ear buzzing?

- Check whether Ear buzzing is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Excedrin:

Excedrin (22,739 reports)

Ear buzzing treatments and more:

Ear buzzing (58,543 reports)

How severe was Ear buzzing and when was it recovered:

Ear buzzing in Excedrin

Expand to all the drugs that have ingredients of acetaminophen; aspirin; caffeine:

Ear buzzing and drugs with ingredients of acetaminophen; aspirin; caffeine (139 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Excedrin side effects:

Excedrin side effect: Migraine (headache) (834 reports)

Browse all side effects of Excedrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Ear buzzing:

Browse all the drugs that are associated with Ear buzzing:

Ear buzzing (2,356 drugs)

Common conditions associated with Ear buzzing:

Browse all the conditions that are associated with Ear buzzing:

Ear buzzing (3,091 conditions)

Drugs similar to Excedrin and Ear buzzing :

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; aspirin; caffeine (the active ingredients of Excedrin) and Excedrin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.