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Lamotrigine Vs. Celecoxib for a male patient aged 27 (an AI-powered real world drug study)

Summary:

This is a personalized comparison of Lamotrigine, Celecoxib for a man aged 27. The study is created by eHealthMe based on reports from the FDA and eHealthme.

On Jan, 28, 2026

6,080 males aged 27 (±5) who take Lamotrigine, Celecoxib and have adverse effects are studied.

Number of reports submitted per year:

Lamotrigine, Celecoxib for a male patient aged 27.

Information of the patient in this study:

  • Age: 27
  • Gender: male

What are the drugs?

What is the reason to compare the drugs?

  • Bipolar 2 (characterized by at least one episode of hypomania and at least one episode of major depression) is found to be associated with 104 drugs and 362 conditions by eHealthMe. Check the latest studies of Bipolar 2.

eHealthMe real world results:

Most common side effects:

Lamotrigine:

  1. Drug Ineffective
  2. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  3. Rash
  4. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  5. Completed Suicide (act of taking one's own life)
  6. Pyrexia (fever)
  7. Vomiting
  8. Depression
  9. Nausea (feeling of having an urge to vomit)
  10. Anxiety

Celecoxib:

  1. Drug Ineffective
  2. Nausea (feeling of having an urge to vomit)
  3. Back Pain
  4. Fatigue (feeling of tiredness)
  5. Arthralgia (joint pain)
  6. Anxiety
  7. Depression
  8. Insomnia (sleeplessness)
  9. Vomiting
  10. Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

Most common side effects experienced by people in long term (1+ years) use:

Lamotrigine:

  1. Dizziness
  2. Depression
  3. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  4. Rash
  5. Erectile Dysfunction
  6. Fatigue (feeling of tiredness)
  7. Somnolence (a state of near-sleep, a strong desire for sleep)
  8. Weight Increased
  9. Fall
  10. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

Celecoxib:

  1. Depression
  2. Appendicitis (inflammation of the appendix)
  3. Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  4. Viral Upper Respiratory Tract Infection
  5. Nasopharyngitis (inflammation of the nasopharynx)
  6. Hypertension (high blood pressure)
  7. Chest Pain
  8. Cellulitis (infection under the skin)
  9. Back Pain
  10. Acute Myocardial Infarction (acute heart attack)

Drug effectiveness:

Lamotrigine:

  • not at all: 3.86 %
  • somewhat: 14.05 %
  • moderate: 28.37 %
  • high: 32.23 %
  • very high: 21.49 %

Celecoxib:

  • not at all: 7.94 %
  • somewhat: 28.57 %
  • moderate: 46.03 %
  • high: 15.87 %
  • very high: 1.5899999999999999 %


How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

Related publications that referenced our studies

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How the study uses the data?

The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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