Exforge and Syncope - a phase IV clinical study of FDA data

Summary:

Syncope is reported as a side effect among people who take Exforge (amlodipine besylate; valsartan), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Diovan, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Syncope when taking Exforge. It is created by eHealthMe based on reports of 12,942 people who have side effects when taking Exforge from the FDA, and is updated regularly.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

What is Syncope?

Syncope (loss of consciousness with an inability to maintain postural tone) is found to be associated with 3,492 drugs and 3,495 conditions by eHealthMe. Check the latest studies of Syncope.

On Dec, 28, 2025

12,942 people reported to have side effects when taking Exforge.
Among them, 146 people (1.13%) have Syncope.

Among these 146 people:

* Approximation only. Some reports may have incomplete information.

Do you take Exforge and have Syncope?

- Check whether Syncope is associated with a drug or a condition (FREE)
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Exforge:

Exforge (13,350 reports)

Syncope treatments and more:

Syncope (131,320 reports)

How severe was Syncope and when was it recovered:

Syncope in Exforge

Expand to all the drugs that have ingredients of amlodipine besylate; valsartan:

Syncope and drugs with ingredients of amlodipine besylate; valsartan (157 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Exforge side effects:

Browse all side effects of Exforge:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Syncope:

Browse all the drugs that are associated with Syncope:

Syncope (3,492 drugs)

Common conditions associated with Syncope:

Hypertension: 10,426 reports
Hbp: 10,330 reports
Primary pulmonary hypertension: 5,678 reports
Depression aggravated: 3,839 reports
Antidepressant therapy: 3,811 reports
Rheumatoid arthritis: 3,775 reports
Ms: 3,722 reports
Pain: 3,407 reports
Alternative medicine - pain relief: 3,324 reports
Plasmacytoma of bone: 2,888 reports

Browse all the conditions that are associated with Syncope:

Syncope (3,495 conditions)

Drugs similar to Exforge and Syncope :

Related publications that referenced our studies

Dubrey SW, VanGriethuysen J, Edwards CM, "A hairy fall: syncope resulting from topical application of minoxidil", BMJ case reports, 2015 Sep .
Dubrey SW, VanGriethuysen J, Edwards CM, "A hairy fall: syncope resulting from topical application of minoxidil", BMJ case reports, 2015 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate; valsartan (the active ingredients of Exforge) and Exforge (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.