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Exidine and Subcutaneous nodule - a phase IV clinical study of FDA data

Summary:

Subcutaneous nodule is reported as a side effect among people who take Exidine (chlorhexidine gluconate), especially for people who are male, 60+ old, also take Aredia, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Subcutaneous nodule when taking Exidine. It is created by eHealthMe based on reports of 17,245 people who have side effects when taking Exidine from the FDA, and is updated regularly.

What is Exidine?

Exidine has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 17,299 Exidine users. Check the latest studies of Exidine.

What is Subcutaneous nodule?

Subcutaneous nodule is found to be associated with 185 drugs and 263 conditions by eHealthMe. Check the latest studies of Subcutaneous nodule.

On Jul, 06, 2026

17,245 people reported to have side effects when taking Exidine.
Among them, 23 people (0.13%) have Subcutaneous nodule.

Could Exidine cause Subcutaneous nodule?

Among these 23 people:

What is the gender of people who have Subcutaneous nodule when taking Exidine? *

  • female: 17.39 %
  • male: 82.61 %

What is the age of people who have Subcutaneous nodule when taking Exidine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Exidine? *

  1. Zometa: 23 people, 100.00%
  2. Aredia: 23 people, 100.00%
  3. Levaquin: 21 people, 91.30%
  4. Celexa: 20 people, 86.96%
  5. Prozac: 20 people, 86.96%
  6. Centrum: 19 people, 82.61%
  7. Amoxicillin And Clavulanate Potassium: 19 people, 82.61%
  8. Zithromax: 19 people, 82.61%
  9. Apresoline: 17 people, 73.91%
  10. Flomax: 17 people, 73.91%

What are other side effects people have besides Subcutaneous nodule? *

  1. Anaemia (lack of blood): 23 people, 100.00%
  2. Stress And Anxiety: 23 people, 100.00%
  3. Osteopenia (a condition where bone mineral density is lower than normal): 23 people, 100.00%
  4. Decreased Interest: 23 people, 100.00%
  5. Osteonecrosis Of Jaw (death of bone of jaw): 23 people, 100.00%
  6. Sensitivity Of Teeth: 23 people, 100.00%
  7. Osteomyelitis (infection of bone): 23 people, 100.00%
  8. General Physical Health Deterioration (weak health status): 23 people, 100.00%
  9. Cerebral Atrophy (decrement in size of brain): 23 people, 100.00%
  10. Spinal Osteoarthritis (joint cartilage loss in spine): 23 people, 100.00%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 19 people, 82.61%

* Approximation only. Some reports may have incomplete information.

Do you take Exidine and have Subcutaneous nodule?

- Check whether Subcutaneous nodule is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Exidine:

Subcutaneous nodule treatments and more:

How severe was Subcutaneous nodule and when was it recovered:

Expand to all the drugs that have ingredients of chlorhexidine gluconate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Exidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Subcutaneous nodule:

Browse all the conditions that are associated with Subcutaneous nodule:

How the study uses the data?

The study uses data from the FDA. It is based on chlorhexidine gluconate (the active ingredients of Exidine) and Exidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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