Sotret and Constipation - a phase IV clinical study of FDA data
Summary:
Constipation is reported as a side effect among people who take Sotret (isotretinoin), especially for people who are female, 10-19 old, have been taking the drug for < 1 month also take Accutane, and have Astrocytoma, low grade.
The phase IV clinical study analyzes which people have Constipation when taking Sotret. It is created by eHealthMe based on reports of 8,745 people who have side effects when taking Sotret from the FDA, and is updated regularly.
What is Sotret?
Sotret has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 9,023 Sotret users. Check the latest studies of Sotret.
What is Constipation?
Constipation is found to be associated with 3,004 drugs and 4,611 conditions by eHealthMe. Check the latest studies of Constipation.
8,745 people reported to have side effects when taking Sotret.
Among them, 37 people (0.42%) have Constipation.

Among these 37 people:
How long have people been on Sotret when they have Constipation? *
- < 1 month: 36.36 %
- 1 - 6 months: 27.27 %
- 6 - 12 months: 27.27 %
- 1 - 2 years: 9.09 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Constipation when taking Sotret? *
- female: 62.5 %
- male: 37.5 %
What is the age of people who have Constipation when taking Sotret? *
- 0-1: 0.0 %
- 2-9: 7.69 %
- 10-19: 38.46 %
- 20-29: 34.62 %
- 30-39: 3.85 %
- 40-49: 0.0 %
- 50-59: 0.0 %
- 60+: 15.38 %
What are other drugs people take besides Sotret? *
- Accutane: 4 people, 10.81%
- Rapamune: 3 people, 8.11%
- Afinitor: 3 people, 8.11%
- Amnesteem: 3 people, 8.11%
- Aspirin: 3 people, 8.11%
- Carbatrol: 3 people, 8.11%
- Zenatane: 3 people, 8.11%
- Rivastigmine Tartrate: 2 people, 5.41%
- Midodrine Hydrochloride: 2 people, 5.41%
- Carbidopa And Levodopa: 2 people, 5.41%
What are other side effects people have besides Constipation? *
- Diarrhea: 11 people, 29.73%
- Dry Skin: 9 people, 24.32%
- Fatigue (feeling of tiredness): 9 people, 24.32%
- Rashes (redness): 8 people, 21.62%
- Headache (pain in head): 7 people, 18.92%
- Joint Pain: 6 people, 16.22%
- Lip Dry: 6 people, 16.22%
- Pain In Extremity: 5 people, 13.51%
- Nausea (feeling of having an urge to vomit): 5 people, 13.51%
- Memory Loss: 5 people, 13.51%
What are the existing conditions these people have? *
- Astrocytoma, Low Grade (low grade tumour of the brain that originate in a particular kind of glial-cells): 3 people, 8.11%
- Parkinson's Disease: 2 people, 5.41%
- Neuroblastoma Recurrent (reoccurrence of a cancer that forms in your nerve tissue): 2 people, 5.41%
- Hyperhidrosis (abnormally increased sweating): 2 people, 5.41%
- Hallucinations (sensations that appear real but are created by your mind): 2 people, 5.41%
- Delusion (a false belief or opinion): 2 people, 5.41%
- Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 5.41%
- Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 5.41%
- Ovarian Cancer (cancer of ovary): 1 person, 2.70%
- Neuroblastoma (a cancer that forms in your nerve tissue): 1 person, 2.70%
* Approximation only. Some reports may have incomplete information.
Do you take Sotret and have Constipation?
- Check whether Constipation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Sotret:
- Sotret (9,023 reports)
Constipation treatments and more:
- Constipation (337,879 reports)
How severe was Constipation and when was it recovered:
Expand to all the drugs that have ingredients of isotretinoin:
- Constipation and drugs with ingredients of isotretinoin (730 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Sotret:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Constipation:
- Constipation (3,004 drugs)
Browse all the conditions that are associated with Constipation:
- Constipation (4,611 conditions)
Related publications that referenced our studies
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on isotretinoin (the active ingredients of Sotret) and Sotret (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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