Exjade and Hypercoagulation - a phase IV clinical study of FDA data

Summary:

Hypercoagulation is reported as a side effect among people who take Exjade (deferasirox), especially for people who are female, 10-19 old, also take Hydrea, and have Graft versus host disease.

The phase IV clinical study analyzes which people have Hypercoagulation when taking Exjade. It is created by eHealthMe based on reports of 29,418 people who have side effects when taking Exjade from the FDA, and is updated regularly.

What is Exjade?

Exjade has active ingredients of deferasirox. It is often used in iron overload. eHealthMe is studying from 29,456 Exjade users. Check the latest studies of Exjade.

What is Hypercoagulation?

Hypercoagulation (increased tendency for clotting of the blood) is found to be associated with 419 drugs and 535 conditions by eHealthMe. Check the latest studies of Hypercoagulation.

On Jan, 30, 2026

29,418 people reported to have side effects when taking Exjade.
Among them, 8 people (0.03%) have Hypercoagulation.

Among these 8 people:

What is the gender of people who have Hypercoagulation when taking Exjade? *

female: 62.5 %
male: 37.5 %

What is the age of people who have Hypercoagulation when taking Exjade? *

What are other drugs people take besides Exjade? *

What are other side effects people have besides Hypercoagulation? *

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 50.00%
Speech Disorder: 3 people, 37.50%
Abdominal Pain: 3 people, 37.50%
Vasodilatation (widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls): 3 people, 37.50%
Vascular Fragility (high risk of complications from surgery): 3 people, 37.50%
Urination - Painful: 3 people, 37.50%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 37.50%
Moyamoya Disease (a disease in which certain arteries in the brain are constricted. blood flow is blocked by the constriction): 3 people, 37.50%
Serum Ferritin Increased: 3 people, 37.50%
Oxygen Saturation Decreased: 3 people, 37.50%

What are the existing conditions these people have? *

Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 1 person, 12.50%
Pain: 1 person, 12.50%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 12.50%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Exjade and have Hypercoagulation?

- Check whether Hypercoagulation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Exjade:

Exjade (29,456 reports)

Browse all side effects of Exjade:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypercoagulation:

Hypercoagulation (419 drugs)

Browse all the conditions that are associated with Hypercoagulation:

Hypercoagulation (535 conditions)

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on deferasirox (the active ingredients of Exjade) and Exjade (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.