Eylea and Confusion - a phase IV clinical study of FDA data

Summary:

Confusion is reported as a side effect among people who take Eylea (aflibercept), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lucentis, and have Age-related macular degeneration.

The phase IV clinical study analyzes which people have Confusion when taking Eylea. It is created by eHealthMe based on reports of 27,819 people who have side effects when taking Eylea from the FDA, and is updated regularly.

What is Eylea?

Eylea has active ingredients of aflibercept. It is often used in macular degeneration. eHealthMe is studying from 27,868 Eylea users. Check the latest studies of Eylea.

What is Confusion?

Confusion is found to be associated with 1,834 drugs and 2,829 conditions by eHealthMe. Check the latest studies of Confusion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

27,819 people reported to have side effects when taking Eylea.
Among them, 25 people (0.09%) have Confusion.

Among these 25 people:

How long have people been on Eylea when they have Confusion? *

What is the gender of people who have Confusion when taking Eylea? *

female: 60 %
male: 40 %

What is the age of people who have Confusion when taking Eylea? *

What are other drugs people take besides Eylea? *

What are other side effects people have besides Confusion? *

Drowsiness: 5 people, 20.00%
Loss Of Consciousness: 4 people, 16.00%
Confusional State: 3 people, 12.00%
Vision Blurred: 3 people, 12.00%
Eye Pain: 3 people, 12.00%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 12.00%
Vitreous Floaters (spots before the eyes): 2 people, 8.00%
Fever: 2 people, 8.00%
Headache (pain in head): 2 people, 8.00%
Injection Related Reaction: 2 people, 8.00%

What are the existing conditions these people have? *

Age-Related Macular Degeneration: 8 people, 32.00%
Retinal Vessel Occlusion (a blockage in one of the small arteries): 3 people, 12.00%
Retinal Vascular Occlusion (a blockage of the small veins that carry blood away from the retina): 1 person, 4.00%
Presumed Ocular Histoplasmosis Syndrome (syndrome affecting the eye): 1 person, 4.00%
Pain: 1 person, 4.00%
Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 1 person, 4.00%
High Blood Pressure: 1 person, 4.00%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 1 person, 4.00%
Constipation: 1 person, 4.00%
Choroidal Neovascularisation (creation of new blood vessels in vascular layer of eye): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Eylea and have Confusion?

- Check whether Confusion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Eylea:

Eylea (27,868 reports)

Confusion treatments and more:

Confusion (65,238 reports)

Browse all side effects of Eylea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Confusion:

Confusion (1,834 drugs)

Browse all the conditions that are associated with Confusion:

Confusion (2,829 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aflibercept (the active ingredients of Eylea) and Eylea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.