Eylea and Therapeutic response unexpected - a phase IV clinical study of FDA data

Summary:

Therapeutic response unexpected is reported as a side effect among people who take Eylea (aflibercept), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Baby Aspirin, and have Age-related macular degeneration.

The phase IV clinical study analyzes which people have Therapeutic response unexpected when taking Eylea. It is created by eHealthMe based on reports of 27,819 people who have side effects when taking Eylea from the FDA, and is updated regularly.

What is Eylea?

Eylea has active ingredients of aflibercept. It is often used in macular degeneration. eHealthMe is studying from 27,868 Eylea users. Check the latest studies of Eylea.

What is Therapeutic response unexpected?

Therapeutic response unexpected is found to be associated with 1,418 drugs and 1,557 conditions by eHealthMe. Check the latest studies of Therapeutic response unexpected.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

27,819 people reported to have side effects when taking Eylea.
Among them, 17 people (0.06%) have Therapeutic response unexpected.

Could Eylea cause Therapeutic response unexpected?

Among these 17 people:

How long have people been on Eylea when they have Therapeutic response unexpected? *

What is the gender of people who have Therapeutic response unexpected when taking Eylea? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Therapeutic response unexpected when taking Eylea? *

What are other drugs people take besides Eylea? *

What are other side effects people have besides Therapeutic response unexpected? *

Weight Increased: 2 people, 11.76%
Blindness: 2 people, 11.76%
Diarrhea: 1 person, 5.88%
Fatigue (feeling of tiredness): 1 person, 5.88%
Fall: 1 person, 5.88%
Eye Swelling: 1 person, 5.88%
Eye Pain: 1 person, 5.88%
Eye Irritation: 1 person, 5.88%
Eye Haemorrhage (bleeding in the eye): 1 person, 5.88%
Endophthalmitis (inflammation of the internal coats of the eye): 1 person, 5.88%

What are the existing conditions these people have? *

Retinal Vessel Occlusion (a blockage in one of the small arteries): 1 person, 5.88%
Retinal Scar (development of scar tissue on retina): 1 person, 5.88%
Primary Myelofibrosis (primary disorder of the bone marrow): 1 person, 5.88%
Hypersensitivity: 1 person, 5.88%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 1 person, 5.88%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 5.88%
Chorioretinal Atrophy (damaged retina and choroid part of eye): 1 person, 5.88%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 5.88%
Age-Related Macular Degeneration: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Eylea and have Therapeutic response unexpected?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Eylea:

Eylea (27,868 reports)

Browse all side effects of Eylea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Therapeutic response unexpected:

Therapeutic response unexpected (1,418 drugs)

Browse all the conditions that are associated with Therapeutic response unexpected:

Therapeutic response unexpected (1,557 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aflibercept (the active ingredients of Eylea) and Eylea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.