Eylea and Upper respiratory tract infection - a phase IV clinical study of FDA data

Summary:

Upper respiratory tract infection is reported as a side effect among people who take Eylea (aflibercept), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Ventolin, and have Age-related macular degeneration.

The phase IV clinical study analyzes which people have Upper respiratory tract infection when taking Eylea. It is created by eHealthMe based on reports of 27,819 people who have side effects when taking Eylea from the FDA, and is updated regularly.

What is Eylea?

Eylea has active ingredients of aflibercept. It is often used in macular degeneration. eHealthMe is studying from 27,868 Eylea users. Check the latest studies of Eylea.

What is Upper respiratory tract infection?

Upper respiratory tract infection is found to be associated with 1,900 drugs and 1,773 conditions by eHealthMe. Check the latest studies of Upper respiratory tract infection.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

27,819 people reported to have side effects when taking Eylea.
Among them, 14 people (0.05%) have Upper respiratory tract infection.

Could Eylea cause Upper respiratory tract infection?

Among these 14 people:

How long have people been on Eylea when they have Upper respiratory tract infection? *

What is the gender of people who have Upper respiratory tract infection when taking Eylea? *

female: 100 %
male: 0.0 %

What is the age of people who have Upper respiratory tract infection when taking Eylea? *

What are other drugs people take besides Eylea? *

Ventolin: 3 people, 21.43%
Aspirin: 2 people, 14.29%
Zyrtec: 1 person, 7.14%
Combivent: 1 person, 7.14%
Losartan Potassium: 1 person, 7.14%
Lisinopril: 1 person, 7.14%
Klor-Con: 1 person, 7.14%
Flaxseed: 1 person, 7.14%
Epinephrine: 1 person, 7.14%
Diphenhydramine Hydrochloride: 1 person, 7.14%

What are other side effects people have besides Upper respiratory tract infection? *

Fever: 4 people, 28.57%
Malaise (a feeling of general discomfort or uneasiness): 3 people, 21.43%
Dyspnea (difficult or laboured breathing): 3 people, 21.43%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 14.29%
Dengue Fever: 2 people, 14.29%
Headache (pain in head): 2 people, 14.29%
Interstitial Lung Disease: 2 people, 14.29%
Gallbladder Disease: 2 people, 14.29%
Lung Infection: 2 people, 14.29%
Pain: 2 people, 14.29%

What are the existing conditions these people have? *

Age-Related Macular Degeneration: 3 people, 21.43%
Retinal Vessel Occlusion (a blockage in one of the small arteries): 2 people, 14.29%
Sleep Disorder: 1 person, 7.14%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 7.14%
Nausea (feeling of having an urge to vomit): 1 person, 7.14%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.14%
Malaise (a feeling of general discomfort or uneasiness): 1 person, 7.14%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 1 person, 7.14%
Choroidal Neovascularisation (creation of new blood vessels in vascular layer of eye): 1 person, 7.14%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Eylea and have Upper respiratory tract infection?

- Check whether Upper respiratory tract infection is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Eylea:

Eylea (27,868 reports)

Browse all side effects of Eylea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Upper respiratory tract infection:

Upper respiratory tract infection (1,900 drugs)

Browse all the conditions that are associated with Upper respiratory tract infection:

Upper respiratory tract infection (1,773 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aflibercept (the active ingredients of Eylea) and Eylea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.