Feldene and Bone loss - a phase IV clinical study of FDA data

Summary:

Bone loss is reported as a side effect among people who take Feldene (piroxicam), especially for people who are female, 40-49 old, also take Plaquenil, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Bone loss when taking Feldene. It is created by eHealthMe based on reports of 3,850 people who have side effects when taking Feldene from the FDA, and is updated regularly.

What is Feldene?

Feldene has active ingredients of piroxicam. It is often used in arthritis. eHealthMe is studying from 3,913 Feldene users. Check the latest studies of Feldene.

What is Bone loss?

Bone loss is found to be associated with 696 drugs and 559 conditions by eHealthMe. Check the latest studies of Bone loss.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

3,850 people reported to have side effects when taking Feldene.
Among them, 11 people (0.29%) have Bone loss.

Among these 11 people:

What is the gender of people who have Bone loss when taking Feldene? *

female: 90.91 %
male: 9.09 %

What is the age of people who have Bone loss when taking Feldene? *

What are other drugs people take besides Feldene? *

What are other side effects people have besides Bone loss? *

Rib Fracture: 10 people, 90.91%
Dyspnea (difficult or laboured breathing): 10 people, 90.91%
Stress And Anxiety: 10 people, 90.91%
Gait Disturbance: 9 people, 81.82%
Osteosclerosis (an elevation in bone density): 9 people, 81.82%
Pain In Extremity: 9 people, 81.82%
Depression: 9 people, 81.82%
Foot Fracture: 8 people, 72.73%
Fracture Nonunion (permanent failure of healing following a broken bone): 8 people, 72.73%
Fracture Delayed Union (delayed cure of broken bone): 8 people, 72.73%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 90.91%
Osteoporosis (bones weak and more likely to break): 8 people, 72.73%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 72.73%
Hiv Infection: 1 person, 9.09%
High Blood Pressure: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Feldene and have Bone loss?

- Check whether Bone loss is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Feldene:

Feldene (3,913 reports)

Bone loss treatments and more:

Bone loss (27,142 reports)

Browse all side effects of Feldene:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone loss:

Bone loss (696 drugs)

Browse all the conditions that are associated with Bone loss:

Bone loss (559 conditions)

Related publications that referenced our studies

Kola E, Bakalli I, Celaj E, Lluka R, Heta S, Sallabanda S, "Stomach perforation from piroxicam poisoning", Paediatrics Today, 2012 Jun .
Kola E, Bakalli I, Celaj E, Lluka R, Heta S, Sallabanda S, "Stomach perforation from piroxicam poisoning", Paediatrics Today, 2012 Jun .

How the study uses the data?

The study uses data from the FDA. It is based on piroxicam (the active ingredients of Feldene) and Feldene (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.