Femara and Alveolar osteitis - a phase IV clinical study of FDA data

Summary:

Alveolar osteitis is reported as a side effect among people who take Femara (letrozole), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Zometa, and have Metastases to bone.

The phase IV clinical study analyzes which people have Alveolar osteitis when taking Femara. It is created by eHealthMe based on reports of 19,093 people who have side effects when taking Femara from the FDA, and is updated regularly.

What is Femara?

Femara has active ingredients of letrozole. It is often used in breast cancer. eHealthMe is studying from 19,630 Femara users. Check the latest studies of Femara.

What is Alveolar osteitis?

Alveolar osteitis (complication of wound healing following extraction of a tooth) is found to be associated with 199 drugs and 199 conditions by eHealthMe. Check the latest studies of Alveolar osteitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

19,093 people reported to have side effects when taking Femara.
Among them, 47 people (0.25%) have Alveolar osteitis.

Among these 47 people:

How long have people been on Femara when they have Alveolar osteitis? *

What is the gender of people who have Alveolar osteitis when taking Femara? *

female: 97.87 %
male: 2.13 %

What is the age of people who have Alveolar osteitis when taking Femara? *

What are other drugs people take besides Femara? *

What are other side effects people have besides Alveolar osteitis? *

Pain In Jaw: 38 people, 80.85%
Bone Disorder: 32 people, 68.09%
Osteonecrosis Of Jaw (death of bone of jaw): 31 people, 65.96%
Metastases To Liver (cancer spreads to liver): 30 people, 63.83%
Fatigue (feeling of tiredness): 27 people, 57.45%
Nausea (feeling of having an urge to vomit): 27 people, 57.45%
Nausea And Vomiting: 25 people, 53.19%
Fall: 24 people, 51.06%
Loose Tooth: 23 people, 48.94%
Sinus Disorder (disease of sinus): 22 people, 46.81%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 31 people, 65.96%
Stress And Anxiety: 1 person, 2.13%
Depression: 1 person, 2.13%

* Approximation only. Some reports may have incomplete information.

Do you take Femara and have Alveolar osteitis?

- Check whether Alveolar osteitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Femara:

Femara (19,630 reports)

Browse all side effects of Femara:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Alveolar osteitis:

Alveolar osteitis (199 drugs)

Browse all the conditions that are associated with Alveolar osteitis:

Alveolar osteitis (199 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on letrozole (the active ingredients of Femara) and Femara (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.