Fenofibrate and Necrosis - a phase IV clinical study of FDA data

Summary:

Necrosis is reported as a side effect among people who take Fenofibrate (fenofibrate), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Ampicillin And Sulbactam, and have Meningitis bacterial.

The phase IV clinical study analyzes which people have Necrosis when taking Fenofibrate. It is created by eHealthMe based on reports of 39,402 people who have side effects when taking Fenofibrate from the FDA, and is updated regularly.

What is Fenofibrate?

Fenofibrate has active ingredients of fenofibrate. It is often used in high blood cholesterol. eHealthMe is studying from 40,456 Fenofibrate users. Check the latest studies of Fenofibrate.

What is Necrosis?

Necrosis (the death of body tissue) is found to be associated with 754 drugs and 969 conditions by eHealthMe. Check the latest studies of Necrosis.



On Jul, 21, 2026

39,402 people reported to have side effects when taking Fenofibrate.
Among them, 32 people (0.08%) have Necrosis.

Could Fenofibrate cause Necrosis?

Among these 32 people:

How long have people been on Fenofibrate when they have Necrosis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Necrosis when taking Fenofibrate? *

  • female: 56.67 %
  • male: 43.33 %

What is the age of people who have Necrosis when taking Fenofibrate? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 6.9 %
  • 40-49: 17.24 %
  • 50-59: 13.79 %
  • 60+: 62.07 %

What are other drugs people take besides Fenofibrate? *

  1. Ampicillin And Sulbactam: 5 people, 15.62%
  2. Levothyroxine Sodium: 3 people, 9.38%
  3. Nystatin: 3 people, 9.38%
  4. Hydroxyzine: 3 people, 9.38%
  5. Metformin: 3 people, 9.38%
  6. Simvastatin: 3 people, 9.38%
  7. Levofloxacin: 2 people, 6.25%
  8. Omacor: 2 people, 6.25%
  9. Chantix: 2 people, 6.25%
  10. Escitalopram: 2 people, 6.25%

What are other side effects people have besides Necrosis? *

  1. Hypotension (abnormally low blood pressure): 9 people, 28.12%
  2. Fever: 9 people, 28.12%
  3. Drug Hypersensitivity: 9 people, 28.12%
  4. Oedema (fluid collection in tissue): 9 people, 28.12%
  5. Purpura (purplish discoloration of the skin): 9 people, 28.12%
  6. Abnormal Behavior: 8 people, 25.00%
  7. Hyporesponsive To Stimuli (abnormally low degree of responsiveness on an agent, action, or condition): 8 people, 25.00%
  8. Normochromic Normocytic Anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits): 8 people, 25.00%
  9. Dermatitis Bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid): 8 people, 25.00%
  10. Confusional State: 8 people, 25.00%

What are the existing conditions these people have? *

  1. Meningitis Bacterial (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 8 people, 25.00%
  2. High Blood Pressure: 4 people, 12.50%
  3. Type 2 Diabetes: 4 people, 12.50%
  4. Weight Decreased: 2 people, 6.25%
  5. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 6.25%
  6. Hypotension (abnormally low blood pressure): 2 people, 6.25%
  7. Ill-Defined Disorder: 2 people, 6.25%
  8. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 6.25%
  9. Lymphoma (cancer that begins in immune system cells): 1 person, 3.12%
  10. Insomnia (sleeplessness): 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Fenofibrate and have Necrosis?

- Check whether Necrosis is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fenofibrate:

Necrosis treatments and more:

How severe was Necrosis and when was it recovered:

Expand to all the drugs that have ingredients of fenofibrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fenofibrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Necrosis:

Browse all the conditions that are associated with Necrosis:


How the study uses the data?

The study uses data from the FDA. It is based on fenofibrate (the active ingredients of Fenofibrate) and Fenofibrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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