Flexeril and Arteriosclerosis coronary artery - a phase IV clinical study of FDA data

Summary:

Arteriosclerosis coronary artery is reported as a side effect among people who take Flexeril (cyclobenzaprine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Xanax, and have High blood pressure.

The phase IV clinical study analyzes which people have Arteriosclerosis coronary artery when taking Flexeril. It is created by eHealthMe based on reports of 34,789 people who have side effects when taking Flexeril from the FDA, and is updated regularly.

What is Flexeril?

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 38,308 Flexeril users. Check the latest studies of Flexeril.

What is Arteriosclerosis coronary artery?

Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery) is found to be associated with 875 drugs and 946 conditions by eHealthMe. Check the latest studies of Arteriosclerosis coronary artery.

On Jul, 22, 2026

34,789 people reported to have side effects when taking Flexeril.
Among them, 70 people (0.2%) have Arteriosclerosis coronary artery.

Could Flexeril cause Arteriosclerosis coronary artery?

Among these 70 people:

How long have people been on Flexeril when they have Arteriosclerosis coronary artery? *

What is the gender of people who have Arteriosclerosis coronary artery when taking Flexeril? *

female: 52.94 %
male: 47.06 %

What is the age of people who have Arteriosclerosis coronary artery when taking Flexeril? *

What are other drugs people take besides Flexeril? *

What are other side effects people have besides Arteriosclerosis coronary artery? *

Chest Pain: 26 people, 37.14%
Heart Attack: 23 people, 32.86%
Cardiac Failure Congestive: 22 people, 31.43%
Pain: 18 people, 25.71%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 17 people, 24.29%
Type 2 Diabetes: 17 people, 24.29%
Mitral Valve Incompetence (inefficient heart valve): 16 people, 22.86%
Depression: 16 people, 22.86%
Stress And Anxiety: 15 people, 21.43%
Dizziness: 15 people, 21.43%

What are the existing conditions these people have? *

High Blood Pressure: 21 people, 30.00%
Stress And Anxiety: 15 people, 21.43%
Diabetes: 12 people, 17.14%
Pain: 10 people, 14.29%
Depression: 7 people, 10.00%
Stable Angina (a constant chest pain): 7 people, 10.00%
Affective Disorder (mental disorder): 6 people, 8.57%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 8.57%
Postpartum Depression (depression suffered by a mother following childbirth): 6 people, 8.57%
Disturbance In Attention: 6 people, 8.57%

* Approximation only. Some reports may have incomplete information.

Do you take Flexeril and have Arteriosclerosis coronary artery?

- Check whether Arteriosclerosis coronary artery is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Flexeril:

Flexeril (38,308 reports)

Browse all side effects of Flexeril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Arteriosclerosis coronary artery:

Arteriosclerosis coronary artery (875 drugs)

Browse all the conditions that are associated with Arteriosclerosis coronary artery:

Arteriosclerosis coronary artery (946 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride (the active ingredients of Flexeril) and Flexeril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.