Flexeril and Bedridden - a phase IV clinical study of FDA data

Summary:

Bedridden is reported as a side effect among people who take Flexeril (cyclobenzaprine hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Lyrica, and have Pain.

The phase IV clinical study analyzes which people have Bedridden when taking Flexeril. It is created by eHealthMe based on reports of 34,789 people who have side effects when taking Flexeril from the FDA, and is updated regularly.

What is Flexeril?

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 38,304 Flexeril users. Check the latest studies of Flexeril.

What is Bedridden?

Bedridden is found to be associated with 992 drugs and 1,093 conditions by eHealthMe. Check the latest studies of Bedridden.

On Sep, 14, 2025

34,789 people reported to have side effects when taking Flexeril.
Among them, 76 people (0.22%) have Bedridden.

Among these 76 people:

How long have people been on Flexeril when they have Bedridden? *

What is the gender of people who have Bedridden when taking Flexeril? *

female: 76.06 %
male: 23.94 %

What is the age of people who have Bedridden when taking Flexeril? *

What are other drugs people take besides Flexeril? *

What are other side effects people have besides Bedridden? *

Pain: 43 people, 56.58%
Weakness: 30 people, 39.47%
Stress And Anxiety: 27 people, 35.53%
Depression: 22 people, 28.95%
Weight Decreased: 19 people, 25.00%
Injury: 19 people, 25.00%
Hypoaesthesia (reduced sense of touch or sensation): 18 people, 23.68%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 18 people, 23.68%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 17 people, 22.37%
Malaise (a feeling of general discomfort or uneasiness): 16 people, 21.05%

What are the existing conditions these people have? *

Pain: 16 people, 21.05%
Neoplasm Malignant (cancer tumour): 10 people, 13.16%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 10.53%
Stress And Anxiety: 7 people, 9.21%
Multiple Myeloma (cancer of the plasma cells): 7 people, 9.21%
Migraine (headache): 7 people, 9.21%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 7.89%
Insomnia (sleeplessness): 6 people, 7.89%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 5.26%
Gastritis (inflammation of stomach): 4 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Flexeril and have Bedridden?

- Check whether Bedridden is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Flexeril:

Flexeril (38,304 reports)

Bedridden treatments and more:

Bedridden (14,887 reports)

How severe was Bedridden and when was it recovered:

Bedridden in Flexeril

Browse all side effects of Flexeril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bedridden:

Bedridden (992 drugs)

Browse all the conditions that are associated with Bedridden:

Bedridden (1,093 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride (the active ingredients of Flexeril) and Flexeril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.