Flexeril and Blushing - a phase IV clinical study of FDA data

Summary:

Blushing is reported as a side effect among people who take Flexeril (cyclobenzaprine hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Tecfidera, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Blushing when taking Flexeril. It is created by eHealthMe based on reports of 34,789 people who have side effects when taking Flexeril from the FDA, and is updated regularly.

What is Flexeril?

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 38,304 Flexeril users. Check the latest studies of Flexeril.

What is Blushing?

Blushing is found to be associated with 3,341 drugs and 2,892 conditions by eHealthMe. Check the latest studies of Blushing.

On Oct, 06, 2025

34,789 people reported to have side effects when taking Flexeril.
Among them, 356 people (1.02%) have Blushing.

Among these 356 people:

How long have people been on Flexeril when they have Blushing? *

What is the gender of people who have Blushing when taking Flexeril? *

female: 71.39 %
male: 28.61 %

What is the age of people who have Blushing when taking Flexeril? *

What are other drugs people take besides Flexeril? *

What are other side effects people have besides Blushing? *

Nausea (feeling of having an urge to vomit): 66 people, 18.54%
Dizziness: 63 people, 17.70%
Headache (pain in head): 62 people, 17.42%
Itching: 59 people, 16.57%
Diarrhea: 57 people, 16.01%
Dyspnea (difficult or laboured breathing): 53 people, 14.89%
Fatigue (feeling of tiredness): 46 people, 12.92%
Hyperhidrosis (abnormally increased sweating): 42 people, 11.80%
Rashes (redness): 40 people, 11.24%
Nausea And Vomiting: 39 people, 10.96%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 103 people, 28.93%
High Blood Cholesterol: 47 people, 13.20%
Pain: 31 people, 8.71%
High Density Lipoprotein Decreased: 19 people, 5.34%
High Blood Pressure: 17 people, 4.78%
Fibromyalgia (a long-term condition which causes pain all over the body): 15 people, 4.21%
Stress And Anxiety: 14 people, 3.93%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 14 people, 3.93%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 13 people, 3.65%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 12 people, 3.37%

* Approximation only. Some reports may have incomplete information.

Do you take Flexeril and have Blushing?

- Check whether Blushing is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Flexeril:

Flexeril (38,304 reports)

Blushing treatments and more:

Blushing (117,674 reports)

Browse all side effects of Flexeril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Blushing:

Browse all the drugs that are associated with Blushing:

Blushing (3,341 drugs)

Common conditions associated with Blushing:

Ms hug: 22,392 reports
Dyslipidemia: 11,125 reports
Lipoprotein test: 11,039 reports
Reduce cholesterol: 10,836 reports
Lipid profile: 10,700 reports
Lower cholesterol: 10,648 reports
Primary pulmonary hypertension: 6,234 reports
High density lipoprotein decreased: 4,574 reports
Hypertension: 3,292 reports
Blood pressure - high: 3,262 reports

Browse all the conditions that are associated with Blushing:

Blushing (2,892 conditions)

Drugs similar to Flexeril and Blushing :

How the study uses the data?

The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride (the active ingredients of Flexeril) and Flexeril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.