Flexeril and Copd - a phase IV clinical study of FDA data

Summary:

Copd is reported as a side effect among people who take Flexeril (cyclobenzaprine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Neurontin, and have Pain.

The phase IV clinical study analyzes which people have Copd when taking Flexeril. It is created by eHealthMe based on reports of 34,789 people who have side effects when taking Flexeril from the FDA, and is updated regularly.

What is Flexeril?

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 38,305 Flexeril users. Check the latest studies of Flexeril.

What is Copd?

Copd (chronic obstructive pulmonary disease) is found to be associated with 1,900 drugs and 2,176 conditions by eHealthMe. Check the latest studies of Copd.

On Sep, 22, 2025

34,789 people reported to have side effects when taking Flexeril.
Among them, 537 people (1.54%) have Copd.

Among these 537 people:

How long have people been on Flexeril when they have Copd? *

What is the gender of people who have Copd when taking Flexeril? *

female: 73.7 %
male: 26.3 %

What is the age of people who have Copd when taking Flexeril? *

What are other drugs people take besides Flexeril? *

What are other side effects people have besides Copd? *

Dyspnea (difficult or laboured breathing): 194 people, 36.13%
Pain: 187 people, 34.82%
Stress And Anxiety: 179 people, 33.33%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 161 people, 29.98%
Pneumonia: 156 people, 29.05%
Fatigue (feeling of tiredness): 145 people, 27.00%
Chest Pain: 144 people, 26.82%
Osteonecrosis Of Jaw (death of bone of jaw): 141 people, 26.26%
Joint Pain: 136 people, 25.33%
Anaemia (lack of blood): 135 people, 25.14%

What are the existing conditions these people have? *

Pain: 88 people, 16.39%
Osteoporosis (bones weak and more likely to break): 83 people, 15.46%
Depression: 55 people, 10.24%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 55 people, 10.24%
High Blood Pressure: 49 people, 9.12%
Stress And Anxiety: 45 people, 8.38%
Metastases To Bone (cancer spreads to bone): 37 people, 6.89%
Diabetes: 35 people, 6.52%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 34 people, 6.33%
High Blood Cholesterol: 33 people, 6.15%

* Approximation only. Some reports may have incomplete information.

Do you take Flexeril and have Copd?

- Check whether Copd is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Flexeril:

Flexeril (38,305 reports)

Copd treatments and more:

Copd (198,238 reports)

Browse all side effects of Flexeril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Copd:

Spiriva side effect: Copd (7,848 reports)
Prednisone side effect: Copd (6,676 reports)
Aspirin side effect: Copd (5,409 reports)
Symbicort side effect: Copd (5,257 reports)
Albuterol side effect: Copd (4,859 reports)
Furosemide side effect: Copd (3,163 reports)
Lasix side effect: Copd (2,971 reports)
Fosamax side effect: Copd (2,963 reports)
Omeprazole side effect: Copd (2,708 reports)
Lisinopril side effect: Copd (2,650 reports)

Browse all the drugs that are associated with Copd:

Copd (1,900 drugs)

Common conditions associated with Copd:

Copd: 9,294 reports
Chronic obstructive pulmonary disease: 8,713 reports
Chronic obstructive lung disease: 4,882 reports
Chronic obstructive airway disease: 4,861 reports
Rheumatoid arthritis: 4,491 reports
Asthma: 4,338 reports
Chronic asthma: 4,332 reports
Osteoporosis: 3,554 reports
Blood pressure - high: 3,516 reports
Thin bones: 3,431 reports

Browse all the conditions that are associated with Copd:

Copd (2,176 conditions)

Drugs similar to Flexeril and Copd :

How the study uses the data?

The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride (the active ingredients of Flexeril) and Flexeril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.