Flexeril and Dependence - from FDA reports


Dependence is found among people who take Flexeril, especially for people who are female, 40-49 old also take medication Xanax, and have Back pain. This review analyzes which people have Dependence with Flexeril. It is created by eHealthMe based on reports of 24,193 people who have side effects when taking Flexeril from FDA , and is updated regularly.

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If you take Flexeril and have Dependence, find out what symptoms you could have in 1 year or longer.

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On Nov, 17, 2017

24,193 people reported to have side effects when taking Flexeril.
Among them, 47 people (0.19%) have Dependence

Number of reports submitted per year:

Could Flexeril cause Dependence?

Gender of people who have Dependence when taking Flexeril *:

  • female: 85.11 %
  • male: 14.89 %

Age of people who have Dependence when taking Flexeril *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 25.0 %
  • 30-39: 25.0 %
  • 40-49: 37.5 %
  • 50-59: 12.5 %
  • 60+: 0.0 %

Top conditions involved for these people *:

  • Back Pain (17 people, 36.17%)
  • Stress And Anxiety (13 people, 27.66%)
  • Pain (11 people, 23.40%)
  • Migraine (9 people, 19.15%)
  • Restless Leg Syndrome (8 people, 17.02%)

Top co-used drugs for these people *:

  • Xanax (21 people, 44.68%)
  • Lortab (20 people, 42.55%)
  • Stadol (18 people, 38.30%)
  • Valium (16 people, 34.04%)
  • Ambien (16 people, 34.04%)

Top other side effects for these people *:

  • Stress And Anxiety (25 people, 53.19%)
  • Depression (25 people, 53.19%)
  • Drug Withdrawal Syndrome (19 people, 40.43%)
  • Agitation (12 people, 25.53%)
  • Mood Swings (11 people, 23.40%)

* Approximation only. Some reports may have incomplete information.

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Do you have Dependence when taking Flexeril?

Expand the study to include all drugs with the same ingredients

Dependence and drugs with ingredients of cyclobenzaprine hydrochloride.

Expand the study to include reports from both FDA and eHealthMe

Dependence and Flexeril from FDA and eHealthMe reports


Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. (latest outcomes from Flexeril 27,239 users)


Dependence has been reported by people with migraine, quit smoking, depression, pain, stress and anxiety (latest reports from 5,572 Dependence patients).

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Drugs that are associated with Dependence


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What would happen?

Forecast new side effects and undetected conditions when you take Flexeril and have Dependence.

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