Flexeril and Gastric polyps - a phase IV clinical study of FDA data

Summary:

Gastric polyps is reported as a side effect among people who take Flexeril (cyclobenzaprine hydrochloride), especially for people who are male, 40-49 old, also take Neurontin, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Gastric polyps when taking Flexeril. It is created by eHealthMe based on reports of 34,789 people who have side effects when taking Flexeril from the FDA, and is updated regularly.

What is Flexeril?

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 38,308 Flexeril users. Check the latest studies of Flexeril.

What is Gastric polyps?

Gastric polyps (abnormal growth of stomach tissue projecting from a mucous membrane) is found to be associated with 460 drugs and 488 conditions by eHealthMe. Check the latest studies of Gastric polyps.

On Jul, 24, 2026

34,789 people reported to have side effects when taking Flexeril.
Among them, 22 people (0.06%) have Gastric polyps.

Among these 22 people:

What is the gender of people who have Gastric polyps when taking Flexeril? *

female: 40.91 %
male: 59.09 %

What is the age of people who have Gastric polyps when taking Flexeril? *

What are other drugs people take besides Flexeril? *

Medrol: 12 people, 54.55%
Neurontin: 12 people, 54.55%
Benazepril Hydrochloride: 11 people, 50.00%
Prevacid: 11 people, 50.00%
Protonix: 11 people, 50.00%
Cymbalta: 11 people, 50.00%
Valium: 11 people, 50.00%
Zometa: 11 people, 50.00%
Zithromax: 11 people, 50.00%
Bactrim: 11 people, 50.00%

What are other side effects people have besides Gastric polyps? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 63.64%
Fatigue (feeling of tiredness): 13 people, 59.09%
Chest Pain: 13 people, 59.09%
Gastritis (inflammation of stomach): 13 people, 59.09%
Swallowing Difficulty: 13 people, 59.09%
High Blood Pressure: 13 people, 59.09%
Nausea (feeling of having an urge to vomit): 13 people, 59.09%
Pneumonia: 12 people, 54.55%
Intervertebral Disc Degeneration (spinal disc degeneration): 12 people, 54.55%
Hyperlipidaemia (presence of excess lipids in the blood): 12 people, 54.55%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 13.64%
Stress And Anxiety: 2 people, 9.09%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 9.09%
Depression: 2 people, 9.09%
Pain: 2 people, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 9.09%
Hypokalemia (low potassium): 1 person, 4.55%
High Blood Pressure: 1 person, 4.55%
Histoplasmosis (infection caused by breathing in spores of a fungus): 1 person, 4.55%
Multiple Myeloma (cancer of the plasma cells): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Flexeril and have Gastric polyps?

- Check whether Gastric polyps is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Flexeril:

Flexeril (38,308 reports)

Gastric polyps treatments and more:

Gastric polyps (3,159 reports)

Browse all side effects of Flexeril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gastric polyps:

Gastric polyps (460 drugs)

Browse all the conditions that are associated with Gastric polyps:

Gastric polyps (488 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride (the active ingredients of Flexeril) and Flexeril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.