Flexeril and Stress urinary incontinence - a phase IV clinical study of FDA data

Summary:

Stress urinary incontinence is reported as a side effect among people who take Flexeril (cyclobenzaprine hydrochloride), especially for people who are female, 60+ old, also take Tylenol, and have Pain.

The phase IV clinical study analyzes which people have Stress urinary incontinence when taking Flexeril. It is created by eHealthMe based on reports of 34,789 people who have side effects when taking Flexeril from the FDA, and is updated regularly.

What is Flexeril?

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 38,308 Flexeril users. Check the latest studies of Flexeril.

What is Stress urinary incontinence?

Stress urinary incontinence (leak urine with things like coughing, sneezing or exercise) is found to be associated with 348 drugs and 397 conditions by eHealthMe. Check the latest studies of Stress urinary incontinence.

On Aug, 12, 2026

34,789 people reported to have side effects when taking Flexeril.
Among them, 17 people (0.05%) have Stress urinary incontinence.

Could Flexeril cause Stress urinary incontinence?

Among these 17 people:

What is the gender of people who have Stress urinary incontinence when taking Flexeril? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Stress urinary incontinence when taking Flexeril? *

What are other drugs people take besides Flexeril? *

What are other side effects people have besides Stress urinary incontinence? *

Pain: 11 people, 64.71%
Dizziness: 9 people, 52.94%
Depression: 9 people, 52.94%
Stress And Anxiety: 9 people, 52.94%
Dyspnea (difficult or laboured breathing): 8 people, 47.06%
Anaemia (lack of blood): 8 people, 47.06%
Fatigue (feeling of tiredness): 8 people, 47.06%
Headache (pain in head): 8 people, 47.06%
Sleep Disorder: 8 people, 47.06%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 8 people, 47.06%

What are the existing conditions these people have? *

Pain: 10 people, 58.82%
Sleep Disorder: 5 people, 29.41%
Prostate Cancer Metastatic: 5 people, 29.41%
Chest Pain: 5 people, 29.41%
Neoplasm Malignant (cancer tumour): 5 people, 29.41%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 5 people, 29.41%
High Blood Pressure: 4 people, 23.53%
Prostate Cancer: 4 people, 23.53%
Depression: 4 people, 23.53%
Stress And Anxiety: 3 people, 17.65%

* Approximation only. Some reports may have incomplete information.

Do you take Flexeril and have Stress urinary incontinence?

- Check whether Stress urinary incontinence is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Flexeril:

Flexeril (38,308 reports)

Browse all side effects of Flexeril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stress urinary incontinence:

Stress urinary incontinence (348 drugs)

Browse all the conditions that are associated with Stress urinary incontinence:

Stress urinary incontinence (397 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride (the active ingredients of Flexeril) and Flexeril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.