Flexeril and Thyroide - a phase IV clinical study of FDA data

Summary:

Thyroide is reported as a side effect among people who take Flexeril (cyclobenzaprine hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years also take Synthroid, and have Pain.

The phase IV clinical study analyzes which people have Thyroide when taking Flexeril. It is created by eHealthMe based on reports of 34,789 people who have side effects when taking Flexeril from the FDA, and is updated regularly.

What is Flexeril?

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 38,304 Flexeril users. Check the latest studies of Flexeril.

What is Thyroide?

Thyroide is found to be associated with 1,232 drugs and 1,569 conditions by eHealthMe. Check the latest studies of Thyroide.

On Nov, 24, 2025

34,789 people reported to have side effects when taking Flexeril.
Among them, 103 people (0.3%) have Thyroide.

Among these 103 people:

How long have people been on Flexeril when they have Thyroide? *

What is the gender of people who have Thyroide when taking Flexeril? *

female: 92.23 %
male: 7.77 %

What is the age of people who have Thyroide when taking Flexeril? *

What are other drugs people take besides Flexeril? *

What are other side effects people have besides Thyroide? *

Fatigue (feeling of tiredness): 28 people, 27.18%
Depression: 25 people, 24.27%
Stress And Anxiety: 24 people, 23.30%
Pain: 23 people, 22.33%
Weakness: 22 people, 21.36%
Joint Pain: 22 people, 21.36%
High Blood Pressure: 20 people, 19.42%
Dyspnea (difficult or laboured breathing): 20 people, 19.42%
Chest Pain: 19 people, 18.45%
Anaemia (lack of blood): 18 people, 17.48%

What are the existing conditions these people have? *

Pain: 27 people, 26.21%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 14 people, 13.59%
Asthma: 13 people, 12.62%
Stress And Anxiety: 13 people, 12.62%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 12.62%
Sleep Disorder: 13 people, 12.62%
Depression: 12 people, 11.65%
High Blood Cholesterol: 11 people, 10.68%
High Blood Pressure: 10 people, 9.71%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 8.74%

* Approximation only. Some reports may have incomplete information.

Do you take Flexeril and have Thyroide?

- Check whether Thyroide is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Flexeril:

Flexeril (38,304 reports)

Thyroide treatments and more:

Thyroide (69,453 reports)

Browse all side effects of Flexeril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Thyroide:

Browse all the drugs that are associated with Thyroide:

Thyroide (1,232 drugs)

Common conditions associated with Thyroide:

Arthritis - rheumatoid: 1,897 reports
Multiple sclerosis: 1,590 reports
Hypertension: 1,297 reports
Thyroid disorder: 1,022 reports
Thyroid function test abnormal: 1,020 reports
Hypothyroidism: 1,006 reports
Blood triglycerides abnormal: 848 reports
High blood cholesterol and triglycerides: 844 reports
Lipoprotein test: 797 reports
Osteoporosis: 789 reports

Browse all the conditions that are associated with Thyroide:

Thyroide (1,569 conditions)

Drugs similar to Flexeril and Thyroide :

How the study uses the data?

The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride (the active ingredients of Flexeril) and Flexeril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.