Flovent and Hyperkeratosis - a phase IV clinical study of FDA data

Summary:

Hyperkeratosis is reported as a side effect among people who take Flovent (fluticasone propionate), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Singulair, and have Arthritis.

The phase IV clinical study analyzes which people have Hyperkeratosis when taking Flovent. It is created by eHealthMe based on reports of 44,023 people who have side effects when taking Flovent from the FDA, and is updated regularly.

What is Flovent?

Flovent has active ingredients of fluticasone propionate. It is often used in asthma. eHealthMe is studying from 44,817 Flovent users. Check the latest studies of Flovent.

What is Hyperkeratosis?

Hyperkeratosis (thickening of the outer layer of the skin) is found to be associated with 780 drugs and 771 conditions by eHealthMe. Check the latest studies of Hyperkeratosis.

On Jul, 18, 2026

44,023 people reported to have side effects when taking Flovent.
Among them, 26 people (0.06%) have Hyperkeratosis.

Among these 26 people:

How long have people been on Flovent when they have Hyperkeratosis? *

What is the gender of people who have Hyperkeratosis when taking Flovent? *

female: 52 %
male: 48 %

What is the age of people who have Hyperkeratosis when taking Flovent? *

What are other drugs people take besides Flovent? *

What are other side effects people have besides Hyperkeratosis? *

Joint Pain: 13 people, 50.00%
Chest Pain: 8 people, 30.77%
Fatigue (feeling of tiredness): 7 people, 26.92%
Muscle Aches (muscle pain): 6 people, 23.08%
Rashes (redness): 6 people, 23.08%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 6 people, 23.08%
High Blood Pressure: 5 people, 19.23%
Swelling: 5 people, 19.23%
Hypoaesthesia (reduced sense of touch or sensation): 5 people, 19.23%
Diarrhea: 5 people, 19.23%

What are the existing conditions these people have? *

Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 19.23%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 11.54%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 11.54%
Prostatic Disorder: 3 people, 11.54%
Neuropathy Peripheral (surface nerve damage): 3 people, 11.54%
Muscle Spasms (muscle contraction): 3 people, 11.54%
Dyspnea (difficult or laboured breathing): 3 people, 11.54%
Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 11.54%
Joint Swelling: 2 people, 7.69%
High Blood Pressure: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Flovent and have Hyperkeratosis?

- Check whether Hyperkeratosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Flovent:

Flovent (44,817 reports)

Hyperkeratosis treatments and more:

Hyperkeratosis (8,056 reports)

Browse all side effects of Flovent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperkeratosis:

Hyperkeratosis (780 drugs)

Browse all the conditions that are associated with Hyperkeratosis:

Hyperkeratosis (771 conditions)

Related publications that referenced our studies

Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on fluticasone propionate (the active ingredients of Flovent) and Flovent (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.