Fludara and Cataract - a phase IV clinical study of FDA data
Summary:
Cataract is reported as a side effect among people who take Fludara (fludarabine phosphate), especially for people who are male, 50-59 old, have been taking the drug for 1 - 6 months also take Cyclosporine, and have Chronic graft versus host disease.
The phase IV clinical study analyzes which people have Cataract when taking Fludara. It is created by eHealthMe based on reports of 46,669 people who have side effects when taking Fludara from the FDA, and is updated regularly.
What is Fludara?
Fludara has active ingredients of fludarabine phosphate. eHealthMe is studying from 46,686 Fludara users. Check the latest studies of Fludara.
What is Cataract?
Cataract (clouding of the lens inside the eye) is found to be associated with 1,894 drugs and 2,132 conditions by eHealthMe. Check the latest studies of Cataract.
46,669 people reported to have side effects when taking Fludara.
Among them, 50 people (0.11%) have Cataract.

Among these 50 people:
How long have people been on Fludara when they have Cataract? *
- < 1 month: 0.0 %
- 1 - 6 months: 100 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Cataract when taking Fludara? *
- female: 23.26 %
- male: 76.74 %
What is the age of people who have Cataract when taking Fludara? *
- 0-1: 5.26 %
- 2-9: 2.63 %
- 10-19: 5.26 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 15.79 %
- 50-59: 42.11 %
- 60+: 28.95 %
What are other drugs people take besides Fludara? *
- Cyclosporine: 16 people, 32.00%
- Methotrexate: 15 people, 30.00%
- Acyclovir: 14 people, 28.00%
- Tacrolimus: 13 people, 26.00%
- Thiotepa: 13 people, 26.00%
- Mitomycin: 11 people, 22.00%
- Fluorouracil: 11 people, 22.00%
- Posaconazole: 11 people, 22.00%
- Moxifloxacin: 11 people, 22.00%
- Prednisolone Acetate: 10 people, 20.00%
What are other side effects people have besides Cataract? *
- Osteoporosis (bones weak and more likely to break): 18 people, 36.00%
- Drug Ineffective: 14 people, 28.00%
- Bacterial Infection: 13 people, 26.00%
- Immunodeficiency Disorders: 11 people, 22.00%
- Obstructive Airways Disorder (a progressive disease that makes it hard to breathe): 11 people, 22.00%
- Respiratory Syncytial Virus Infection (viral disease of respiratory system): 11 people, 22.00%
- Chimerism (fertilization of two separate ova by two sperm): 11 people, 22.00%
- Blood Immunoglobulin G Decreased: 11 people, 22.00%
- Acute Kidney Failure: 11 people, 22.00%
- Acute Myeloid Leukaemia Recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent): 11 people, 22.00%
What are the existing conditions these people have? *
- Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 11 people, 22.00%
- Chronic Graft Versus Host Disease (immune cells attack the host's body cells after transplant): 11 people, 22.00%
- Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 9 people, 18.00%
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 7 people, 14.00%
- Immunodeficiency Disorders: 4 people, 8.00%
- Burkitt Lymphoma (cancer of the lymphatic system): 4 people, 8.00%
- Bone Marrow Conditioning Regimen: 3 people, 6.00%
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 3 people, 6.00%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 4.00%
- B-Cell Lymphoma Recurrent (blood cancer affecting b cells-recurrent): 1 person, 2.00%
* Approximation only. Some reports may have incomplete information.
Do you take Fludara and have Cataract?
- Check whether Cataract is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Fludara:
- Fludara (46,686 reports)
Cataract treatments and more:
- Cataract (70,565 reports)
How severe was Cataract and when was it recovered:
Expand to all the drugs that have ingredients of fludarabine phosphate:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Fludara:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Cataract:
- Cataract (1,894 drugs)
Browse all the conditions that are associated with Cataract:
- Cataract (2,132 conditions)
Related publications that referenced our studies
- Lin SY, Lin CL, Ju SW, Wang IK, Lin CC, Lin CH, Hsu WH, Liang JA, "Increasing risk of cataract in HCV patients receiving anti-HCV therapy: A nationwide cohort study", PloS one, 2017 Mar .
- Dsouza MC, "Could risperidone have caused the cataract?: A case report and review of literature", Journal of Research in Psychiatry and Behavioral Science, 2015 Jan .
- Dsouza MC, "COULD RISPERIDONE HAVE CAUSED THE CATARACT", JRPBS, 2015 Jan .
- Lin SY, Lin CL, Ju SW, Wang IK, Lin CC, Lin CH, Hsu WH, Liang JA, "Increasing risk of cataract in HCV patients receiving anti-HCV therapy: A nationwide cohort study", PloS one, 2017 Mar .
- Dsouza MC, "Could risperidone have caused the cataract?: A case report and review of literature", Journal of Research in Psychiatry and Behavioral Science, 2015 Jan .
- Dsouza MC, "COULD RISPERIDONE HAVE CAUSED THE CATARACT", JRPBS, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on fludarabine phosphate (the active ingredients of Fludara) and Fludara (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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