Fluorouracil and Facial paralysis - a phase IV clinical study of FDA data

Summary:

Facial paralysis is reported as a side effect among people who take Fluorouracil (fluorouracil), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Eloxatin, and have Oesophageal squamous cell carcinoma.

The phase IV clinical study analyzes which people have Facial paralysis when taking Fluorouracil. It is created by eHealthMe based on reports of 96,940 people who have side effects when taking Fluorouracil from the FDA, and is updated regularly.

What is Fluorouracil?

Fluorouracil has active ingredients of fluorouracil. It is often used in colon cancer metastatic. eHealthMe is studying from 97,087 Fluorouracil users. Check the latest studies of Fluorouracil.

What is Facial paralysis?

Facial paralysis (loss of function of face muscle) is found to be associated with 661 drugs and 1,151 conditions by eHealthMe. Check the latest studies of Facial paralysis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

96,940 people reported to have side effects when taking Fluorouracil.
Among them, 17 people (0.02%) have Facial paralysis.

Could Fluorouracil cause Facial paralysis?

Among these 17 people:

How long have people been on Fluorouracil when they have Facial paralysis? *

What is the gender of people who have Facial paralysis when taking Fluorouracil? *

female: 12.5 %
male: 87.5 %

What is the age of people who have Facial paralysis when taking Fluorouracil? *

What are other drugs people take besides Fluorouracil? *

What are other side effects people have besides Facial paralysis? *

Speech Impairment (Adult) (inability to speak (adult)): 5 people, 29.41%
Weakness: 4 people, 23.53%
Impaired Gastric Emptying: 3 people, 17.65%
Flat Affect (absence of emotional response to a situation): 3 people, 17.65%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 3 people, 17.65%
Hypophagia (reduced food intake): 2 people, 11.76%
Haemoglobin Decreased: 2 people, 11.76%
Nausea (feeling of having an urge to vomit): 2 people, 11.76%
Postoperative Wound Infection: 2 people, 11.76%
Hemiparesis (weakness on one side of the body): 2 people, 11.76%

What are the existing conditions these people have? *

Oesophageal Squamous Cell Carcinoma (cancer that begins in flat cells lining the oesophagus): 3 people, 17.65%
Metastases To Liver (cancer spreads to liver): 2 people, 11.76%
Rectal Cancer (cancer of rectum): 1 person, 5.88%
Oesophageal Carcinoma (cancer tumour of oesophagus): 1 person, 5.88%
Nasopharyngeal Cancer (cancer of nasopharynx): 1 person, 5.88%
Metastases To Lung (cancer spreads to lung): 1 person, 5.88%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 1 person, 5.88%
Breast Cancer Stage I: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Fluorouracil and have Facial paralysis?

- Check whether Facial paralysis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fluorouracil:

Fluorouracil (97,087 reports)

Browse all side effects of Fluorouracil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Facial paralysis:

Facial paralysis (661 drugs)

Browse all the conditions that are associated with Facial paralysis:

Facial paralysis (1,151 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fluorouracil (the active ingredients of Fluorouracil) and Fluorouracil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.