Fluorouracil and Limb deformity - a phase IV clinical study of FDA data

Summary:

Limb deformity is reported as a side effect among people who take Fluorouracil (fluorouracil), especially for people who are female, 40-49 old, have been taking the drug for 6 - 12 months also take Zofran, and have Colorectal cancer metastatic.

The phase IV clinical study analyzes which people have Limb deformity when taking Fluorouracil. It is created by eHealthMe based on reports of 96,940 people who have side effects when taking Fluorouracil from the FDA, and is updated regularly.

What is Fluorouracil?

Fluorouracil has active ingredients of fluorouracil. It is often used in colon cancer metastatic. eHealthMe is studying from 97,087 Fluorouracil users. Check the latest studies of Fluorouracil.

What is Limb deformity?

Limb deformity (functional disability of leg) is found to be associated with 274 drugs and 337 conditions by eHealthMe. Check the latest studies of Limb deformity.

On Aug, 09, 2026

96,940 people reported to have side effects when taking Fluorouracil.
Among them, 18 people (0.02%) have Limb deformity.

Could Fluorouracil cause Limb deformity?

Among these 18 people:

How long have people been on Fluorouracil when they have Limb deformity? *

What is the gender of people who have Limb deformity when taking Fluorouracil? *

female: 88.24 %
male: 11.76 %

What is the age of people who have Limb deformity when taking Fluorouracil? *

What are other drugs people take besides Fluorouracil? *

What are other side effects people have besides Limb deformity? *

Nausea And Vomiting: 13 people, 72.22%
Wound Dehiscence (a surgical incision reopens either internally or externally): 12 people, 66.67%
Stomatitis (inflammation of mucous membrane of mouth): 12 people, 66.67%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 12 people, 66.67%
Kidney Stones: 12 people, 66.67%
Fatigue (feeling of tiredness): 12 people, 66.67%
Skin Exfoliation (removal of the oldest dead skin cells): 12 people, 66.67%
Drug Intolerance (drug sensitivity): 12 people, 66.67%
Weight Decreased: 12 people, 66.67%
Neuropathy Peripheral (surface nerve damage): 11 people, 61.11%

What are the existing conditions these people have? *

Nasopharyngeal Cancer (cancer of nasopharynx): 2 people, 11.11%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 2 people, 11.11%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.56%
Neoplasm Malignant (cancer tumour): 1 person, 5.56%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 1 person, 5.56%
Metastases To Bone (cancer spreads to bone): 1 person, 5.56%
Indigestion: 1 person, 5.56%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.56%
Colon Cancer: 1 person, 5.56%
Breast Cancer: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Fluorouracil and have Limb deformity?

- Check whether Limb deformity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fluorouracil:

Fluorouracil (97,087 reports)

Limb deformity treatments and more:

Limb deformity (2,271 reports)

Browse all side effects of Fluorouracil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Limb deformity:

Limb deformity (274 drugs)

Browse all the conditions that are associated with Limb deformity:

Limb deformity (337 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fluorouracil (the active ingredients of Fluorouracil) and Fluorouracil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.