Fluorouracil and Rectal stenosis - a phase IV clinical study of FDA data

Summary:

Rectal stenosis is reported as a side effect among people who take Fluorouracil (fluorouracil), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Mercaptopurine, and have Ulcerative colitis.

The phase IV clinical study analyzes which people have Rectal stenosis when taking Fluorouracil. It is created by eHealthMe based on reports of 96,940 people who have side effects when taking Fluorouracil from the FDA, and is updated regularly.

What is Fluorouracil?

Fluorouracil has active ingredients of fluorouracil. It is often used in colon cancer metastatic. eHealthMe is studying from 97,087 Fluorouracil users. Check the latest studies of Fluorouracil.

What is Rectal stenosis?

Rectal stenosis (narrowing of rectum) is found to be associated with 33 drugs and 87 conditions by eHealthMe. Check the latest studies of Rectal stenosis.

On Jul, 13, 2026

96,940 people reported to have side effects when taking Fluorouracil.
Among them, 19 people (0.02%) have Rectal stenosis.

Could Fluorouracil cause Rectal stenosis?

Among these 19 people:

How long have people been on Fluorouracil when they have Rectal stenosis? *

What is the gender of people who have Rectal stenosis when taking Fluorouracil? *

female: 0.0 %
male: 100 %

What is the age of people who have Rectal stenosis when taking Fluorouracil? *

What are other drugs people take besides Fluorouracil? *

What are other side effects people have besides Rectal stenosis? *

Diarrhea: 6 people, 31.58%
Acute Kidney Failure: 5 people, 26.32%
Diarrhea Haemorrhagic: 3 people, 15.79%
Pulmonary Embolism (blockage of the main artery of the lung): 3 people, 15.79%
Febrile Neutropenia (fever with reduced white blood cells): 3 people, 15.79%
Febrile Bone Marrow Aplasia (bone marrow greatly decreases or stops production of blood cells): 3 people, 15.79%
Ureteric Obstruction: 3 people, 15.79%
Enterococcal Infection: 3 people, 15.79%
Linitis Plastica: 3 people, 15.79%
Malignant Pleural Effusion (a condition in which cancer causes an abnormal amount of fluid to collect between the thin layers of tissue lining of lung): 3 people, 15.79%

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 5 people, 26.32%
Rectal Cancer (cancer of rectum): 3 people, 15.79%
Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 2 people, 10.53%
Diabetes: 2 people, 10.53%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 2 people, 10.53%
Colon Cancer: 2 people, 10.53%
Rectal Cancer Stage Iv (rectal cancer has been carried through the lymph system to distant parts of the body): 1 person, 5.26%
Linitis Plastica: 1 person, 5.26%
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Fluorouracil and have Rectal stenosis?

- Check whether Rectal stenosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fluorouracil:

Fluorouracil (97,087 reports)

Browse all side effects of Fluorouracil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rectal stenosis:

Rectal stenosis (33 drugs)

Browse all the conditions that are associated with Rectal stenosis:

Rectal stenosis (87 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fluorouracil (the active ingredients of Fluorouracil) and Fluorouracil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.