Fluoxetine and Concomitant disease aggravated - a phase IV clinical study of FDA data

Summary:

Concomitant disease aggravated is reported as a side effect among people who take Fluoxetine (fluoxetine hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Metformin, and have Acromegaly.

The phase IV clinical study analyzes which people have Concomitant disease aggravated when taking Fluoxetine. It is created by eHealthMe based on reports of 94,370 people who have side effects when taking Fluoxetine from the FDA, and is updated regularly.

What is Fluoxetine?

Fluoxetine has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 98,823 Fluoxetine users. Check the latest studies of Fluoxetine.

What is Concomitant disease aggravated?

Concomitant disease aggravated (advanced due to some of accompanying) is found to be associated with 597 drugs and 631 conditions by eHealthMe. Check the latest studies of Concomitant disease aggravated.

On Jul, 08, 2026

94,370 people reported to have side effects when taking Fluoxetine.
Among them, 73 people (0.08%) have Concomitant disease aggravated.

Could Fluoxetine cause Concomitant disease aggravated?

Among these 73 people:

How long have people been on Fluoxetine when they have Concomitant disease aggravated? *

What is the gender of people who have Concomitant disease aggravated when taking Fluoxetine? *

female: 86.96 %
male: 13.04 %

What is the age of people who have Concomitant disease aggravated when taking Fluoxetine? *

What are other drugs people take besides Fluoxetine? *

What are other side effects people have besides Concomitant disease aggravated? *

Malaise (a feeling of general discomfort or uneasiness): 41 people, 56.16%
Pain: 38 people, 52.05%
Headache (pain in head): 38 people, 52.05%
Memory Loss: 36 people, 49.32%
Fatigue (feeling of tiredness): 32 people, 43.84%
Drug Ineffective: 30 people, 41.10%
Gait Disturbance: 29 people, 39.73%
Joint Pain: 26 people, 35.62%
Head Injury: 26 people, 35.62%
Discomfort: 25 people, 34.25%

What are the existing conditions these people have? *

Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 33 people, 45.21%
Sleep Disorder: 20 people, 27.40%
Diabetes: 20 people, 27.40%
High Blood Pressure: 20 people, 27.40%
Pituitary Tumor: 19 people, 26.03%
Muscle Aches (muscle pain): 14 people, 19.18%
Urinary Tract Disorder: 14 people, 19.18%
Adrenal Disorder: 14 people, 19.18%
Thyroid Diseases: 14 people, 19.18%
Pain: 10 people, 13.70%

* Approximation only. Some reports may have incomplete information.

Do you take Fluoxetine and have Concomitant disease aggravated?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fluoxetine:

Fluoxetine (98,823 reports)

Browse all side effects of Fluoxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Concomitant disease aggravated:

Concomitant disease aggravated (597 drugs)

Browse all the conditions that are associated with Concomitant disease aggravated:

Concomitant disease aggravated (631 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fluoxetine hydrochloride (the active ingredients of Fluoxetine) and Fluoxetine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.