Folate and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Folate (folic acid), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Methotrexate, and have Pain.

The phase IV clinical study analyzes which people have Stroke when taking Folate. It is created by eHealthMe based on reports of 5,953 people who have side effects when taking Folate from the FDA, and is updated regularly.

What is Folate?

Folate has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 6,545 Folate users. Check the latest studies of Folate.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,315 drugs and 3,028 conditions by eHealthMe. Check the latest studies of Stroke.

On Jun, 18, 2026

5,953 people reported to have side effects when taking Folate.
Among them, 54 people (0.91%) have Stroke.

Among these 54 people:

How long have people been on Folate when they have Stroke? *

What is the gender of people who have Stroke when taking Folate? *

female: 56.86 %
male: 43.14 %

What is the age of people who have Stroke when taking Folate? *

What are other drugs people take besides Folate? *

What are other side effects people have besides Stroke? *

Stress And Anxiety: 9 people, 16.67%
Peripheral Swelling: 7 people, 12.96%
Memory Loss: 7 people, 12.96%
Joint Swelling: 6 people, 11.11%
Drug Ineffective: 5 people, 9.26%
Pain: 5 people, 9.26%
Speech Impairment (Adult) (inability to speak (adult)): 5 people, 9.26%
Rashes (redness): 5 people, 9.26%
Joint Range Of Motion Decreased (disease of joint movement): 4 people, 7.41%
Injection Site Pain: 4 people, 7.41%

What are the existing conditions these people have? *

Pain: 10 people, 18.52%
High Blood Pressure: 9 people, 16.67%
Stress And Anxiety: 5 people, 9.26%
Chest Pain: 5 people, 9.26%
Nausea (feeling of having an urge to vomit): 5 people, 9.26%
Infection: 4 people, 7.41%
Blood Pressure Abnormal: 3 people, 5.56%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 5.56%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 5.56%
Multiple Myeloma (cancer of the plasma cells): 3 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Folate and have Stroke?

- Check whether Stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Folate:

Folate (6,545 reports)

Stroke treatments and more:

Stroke (334,635 reports)

Browse all side effects of Folate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Stroke (2,315 drugs)

Browse all the conditions that are associated with Stroke:

Stroke (3,028 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on folic acid (the active ingredients of Folate) and Folate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.