Folic acid and Varicocele - a phase IV clinical study of FDA data

Summary:

Varicocele is reported as a side effect among people who take Folic acid (folic acid), especially for people who are male, 60+ old, also take Klonopin, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Varicocele when taking Folic acid. It is created by eHealthMe based on reports of 162,497 people who have side effects when taking Folic acid from the FDA, and is updated regularly.

What is Folic acid?

Folic acid has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 165,025 Folic acid users. Check the latest studies of Folic acid.

What is Varicocele?

Varicocele (enlarged varicose vein) is found to be associated with 29 drugs and 169 conditions by eHealthMe. Check the latest studies of Varicocele.



On Jul, 18, 2026

162,497 people reported to have side effects when taking Folic acid.
Among them, 11 people (0.01%) have Varicocele.

Could Folic acid cause Varicocele?

Among these 11 people:

What is the gender of people who have Varicocele when taking Folic acid? *

  • female: 0.0 %
  • male: 100 %

What is the age of people who have Varicocele when taking Folic acid? *

  • 0-1: 0.0 %
  • 2-9: 9.09 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 9.09 %
  • 50-59: 0.0 %
  • 60+: 81.82 %

What are other drugs people take besides Folic acid? *

  1. Zometa: 10 people, 90.91%
  2. Aredia: 10 people, 90.91%
  3. Oxycontin: 10 people, 90.91%
  4. Elavil: 10 people, 90.91%
  5. Klonopin: 10 people, 90.91%
  6. Feldene: 9 people, 81.82%
  7. Magnesium: 9 people, 81.82%
  8. Lorazepam: 9 people, 81.82%
  9. Lisinopril: 9 people, 81.82%
  10. Lexapro: 9 people, 81.82%

What are other side effects people have besides Varicocele? *

  1. Anaemia (lack of blood): 10 people, 90.91%
  2. Skin Ulcer: 10 people, 90.91%
  3. Haematochezia (passage of stools containing blood): 10 people, 90.91%
  4. Foot Deformity (functional disability of foot): 10 people, 90.91%
  5. Fall: 10 people, 90.91%
  6. Epididymal Cyst (cyst usually found on the skin): 10 people, 90.91%
  7. Neuralgia (pain in one or more nerves): 10 people, 90.91%
  8. Oedema Peripheral (superficial swelling): 10 people, 90.91%
  9. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 10 people, 90.91%
  10. Osteonecrosis Of Jaw (death of bone of jaw): 10 people, 90.91%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 10 people, 90.91%
  2. Stable Angina (a constant chest pain): 9 people, 81.82%
  3. Depression: 9 people, 81.82%
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints): 9 people, 81.82%
  5. Arrhythmias (irregular heartbeat): 9 people, 81.82%
  6. Osteoporosis (bones weak and more likely to break): 1 person, 9.09%
  7. Inflammation: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Folic acid and have Varicocele?

- Check whether Varicocele is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Folic acid:

Varicocele treatments and more:

How severe was Varicocele and when was it recovered:

Expand to all the drugs that have ingredients of folic acid:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Folic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Varicocele:

Browse all the conditions that are associated with Varicocele:


How the study uses the data?

The study uses data from the FDA. It is based on folic acid (the active ingredients of Folic acid) and Folic acid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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