Fycompa and Hypotension - a phase IV clinical study of FDA data

Summary:

Hypotension is reported as a side effect among people who take Fycompa (perampanel), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Vitamin D, and have Seizures.

The phase IV clinical study analyzes which people have Hypotension when taking Fycompa. It is created by eHealthMe based on reports of 4,363 people who have side effects when taking Fycompa from the FDA, and is updated regularly.

What is Fycompa?

Fycompa has active ingredients of perampanel. eHealthMe is studying from 4,387 Fycompa users. Check the latest studies of Fycompa.

What is Hypotension?

Hypotension (abnormally low blood pressure) is found to be associated with 3,354 drugs and 4,762 conditions by eHealthMe. Check the latest studies of Hypotension.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 24, 2026

4,363 people reported to have side effects when taking Fycompa.
Among them, 55 people (1.26%) have Hypotension.

Could Fycompa cause Hypotension?

Among these 55 people:

How long have people been on Fycompa when they have Hypotension? *

  • < 1 month: 95.83 %
  • 1 - 6 months: 4.17 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypotension when taking Fycompa? *

  • female: 84 %
  • male: 16 %

What is the age of people who have Hypotension when taking Fycompa? *

  • 0-1: 0.0 %
  • 2-9: 2.27 %
  • 10-19: 6.82 %
  • 20-29: 11.36 %
  • 30-39: 0.0 %
  • 40-49: 72.73 %
  • 50-59: 0.0 %
  • 60+: 6.82 %

What are other drugs people take besides Fycompa? *

  1. Vitamin D: 10 people, 18.18%
  2. Keppra: 6 people, 10.91%
  3. Xcopri: 6 people, 10.91%
  4. Lamictal: 6 people, 10.91%
  5. Ativan: 3 people, 5.45%
  6. Midazolam: 3 people, 5.45%
  7. Noxafil: 3 people, 5.45%
  8. Crestor: 3 people, 5.45%
  9. Vfend: 3 people, 5.45%
  10. Tegretol: 3 people, 5.45%

What are other side effects people have besides Hypotension? *

  1. Fatigue (feeling of tiredness): 20 people, 36.36%
  2. Suicidal Ideation: 16 people, 29.09%
  3. Agitation (state of anxiety or nervous excitement): 15 people, 27.27%
  4. Dehydration (dryness resulting from the removal of water): 11 people, 20.00%
  5. Abnormal Behavior: 11 people, 20.00%
  6. Dizziness: 6 people, 10.91%
  7. Drowsiness: 5 people, 9.09%
  8. Pain: 4 people, 7.27%
  9. Fainting (loss of consciousness and postural tone): 4 people, 7.27%
  10. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 7.27%

What are the existing conditions these people have? *

  1. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 10.91%
  2. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 5 people, 9.09%
  3. Aura: 2 people, 3.64%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 3.64%
  5. Partial Seizures (seizures which affect only a part of the brain at onset): 2 people, 3.64%
  6. Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 2 people, 3.64%
  7. Fungal Infection: 2 people, 3.64%
  8. Brain Neoplasm Benign (non-cancerous tumour of brain): 1 person, 1.82%
  9. Chronic Granulomatous Disease (immune system cells are unable to kill some types of bacteria and fungi): 1 person, 1.82%
  10. Constipation: 1 person, 1.82%

* Approximation only. Some reports may have incomplete information.

Do you take Fycompa and have Hypotension?

- Check whether Hypotension is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fycompa:

Hypotension treatments and more:

How severe was Hypotension and when was it recovered:

Expand to all the drugs that have ingredients of perampanel:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fycompa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypotension:

Browse all the conditions that are associated with Hypotension:


How the study uses the data?

The study uses data from the FDA. It is based on perampanel (the active ingredients of Fycompa) and Fycompa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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