Gabapentin and Macule - a phase IV clinical study of FDA data

Summary:

Macule is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Triamcinolone, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Macule when taking Gabapentin. It is created by eHealthMe based on reports of 313,421 people who have side effects when taking Gabapentin from the FDA, and is updated regularly.

What is Gabapentin?

Gabapentin has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 322,983 Gabapentin users. Check the latest studies of Gabapentin.

What is Macule?

Macule (a discoloured spot on the skin) is found to be associated with 297 drugs and 706 conditions by eHealthMe. Check the latest studies of Macule.



On Jul, 16, 2026

313,421 people reported to have side effects when taking Gabapentin.
Among them, 59 people (0.02%) have Macule.

Could Gabapentin cause Macule?

Among these 59 people:

How long have people been on Gabapentin when they have Macule? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Macule when taking Gabapentin? *

  • female: 55.56 %
  • male: 44.44 %

What is the age of people who have Macule when taking Gabapentin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 10.53 %
  • 40-49: 36.84 %
  • 50-59: 21.05 %
  • 60+: 31.58 %

What are other drugs people take besides Gabapentin? *

  1. Triamcinolone: 18 people, 30.51%
  2. Percocet: 14 people, 23.73%
  3. Flexeril: 13 people, 22.03%
  4. Bactrim Ds: 13 people, 22.03%
  5. Atenolol: 13 people, 22.03%
  6. Zometa: 12 people, 20.34%
  7. Compazine: 12 people, 20.34%
  8. Metoclopramide: 11 people, 18.64%
  9. Lyrica: 11 people, 18.64%
  10. Furosemide: 11 people, 18.64%

What are other side effects people have besides Macule? *

  1. Rashes (redness): 25 people, 42.37%
  2. Melanocytic Naevus (a type of lesion that contains nevus cells (a type of melanocyte)): 21 people, 35.59%
  3. Fatigue (feeling of tiredness): 16 people, 27.12%
  4. Blood Glucose Increased: 15 people, 25.42%
  5. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 15 people, 25.42%
  6. Hypoaesthesia (reduced sense of touch or sensation): 15 people, 25.42%
  7. Muscle Aches (muscle pain): 14 people, 23.73%
  8. Itching: 14 people, 23.73%
  9. High Blood Pressure: 14 people, 23.73%
  10. Dyskinesia (abnormality or impairment of voluntary movement): 13 people, 22.03%

What are the existing conditions these people have? *

  1. Stress And Anxiety: 12 people, 20.34%
  2. Psoriasis (immune-mediated disease that affects the skin): 9 people, 15.25%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 11.86%
  4. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5 people, 8.47%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 6.78%
  6. High Blood Cholesterol: 3 people, 5.08%
  7. Primary Myelofibrosis (primary disorder of the bone marrow): 3 people, 5.08%
  8. Bipolar Disorder (mood disorder): 3 people, 5.08%
  9. Depression: 3 people, 5.08%
  10. Multiple Myeloma (cancer of the plasma cells): 3 people, 5.08%

* Approximation only. Some reports may have incomplete information.

Do you take Gabapentin and have Macule?

- Check whether Macule is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Gabapentin:

Macule treatments and more:

How severe was Macule and when was it recovered:

Expand to all the drugs that have ingredients of gabapentin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Gabapentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Macule:

Browse all the conditions that are associated with Macule:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on gabapentin (the active ingredients of Gabapentin) and Gabapentin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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