Gentamicin and Hepatotoxicity - a phase IV clinical study of FDA data

Summary:

Hepatotoxicity is reported as a side effect among people who take Gentamicin (gentamicin sulfate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Vancomycin, and have Endocarditis.

The phase IV clinical study analyzes which people have Hepatotoxicity when taking Gentamicin. It is created by eHealthMe based on reports of 21,523 people who have side effects when taking Gentamicin from the FDA, and is updated regularly.

What is Gentamicin?

Gentamicin has active ingredients of gentamicin sulfate. It is often used in urinary tract infection. eHealthMe is studying from 21,654 Gentamicin users. Check the latest studies of Gentamicin.

What is Hepatotoxicity?

Hepatotoxicity (chemical-driven liver damage) is found to be associated with 1,081 drugs and 1,251 conditions by eHealthMe. Check the latest studies of Hepatotoxicity.

On Aug, 06, 2026

21,523 people reported to have side effects when taking Gentamicin.
Among them, 60 people (0.28%) have Hepatotoxicity.

Among these 60 people:

How long have people been on Gentamicin when they have Hepatotoxicity? *

What is the gender of people who have Hepatotoxicity when taking Gentamicin? *

female: 33.33 %
male: 66.67 %

What is the age of people who have Hepatotoxicity when taking Gentamicin? *

What are other drugs people take besides Gentamicin? *

Vancomycin: 28 people, 46.67%
Heparin: 20 people, 33.33%
Piperacillin And Tazobactam: 14 people, 23.33%
Cefotaxime: 5 people, 8.33%
Linezolid: 5 people, 8.33%
Ampicillin And Sulbactam: 4 people, 6.67%
Vancomycin Hcl: 4 people, 6.67%
Omeprazole: 4 people, 6.67%
Allopurinol: 4 people, 6.67%
Morphine: 4 people, 6.67%

What are other side effects people have besides Hepatotoxicity? *

Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 20 people, 33.33%
Drug Ineffective: 18 people, 30.00%
Weight Decreased: 16 people, 26.67%
Nutritional Condition Abnormal: 16 people, 26.67%
Diarrhea: 16 people, 26.67%
Aspartate Aminotransferase Increased: 10 people, 16.67%
Hepatic Failure (liver failure): 9 people, 15.00%
Alanine Aminotransferase Increased: 9 people, 15.00%
Blood Bilirubin Increased: 6 people, 10.00%
Acute Kidney Failure: 5 people, 8.33%

What are the existing conditions these people have? *

Endocarditis (inflammation in heart muscle): 18 people, 30.00%
Haemarthrosis (haemarthrosis is where blood is able to enter the joint capsule): 17 people, 28.33%
Salmonella Test Positive: 15 people, 25.00%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 15 people, 25.00%
Enterococcal Infection: 13 people, 21.67%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 8 people, 13.33%
Klebsiella Infection: 5 people, 8.33%
Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 4 people, 6.67%
Rash Erythematous (redness of the skin): 4 people, 6.67%
Respiratory Distress Syndrome (Rds) In Infants (respiratory disease of newborn babies, especially premature babies, characterized by distressful breathing, cyanosis, and the formation of a glassy membrane over the alveoli of the lungs): 3 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Gentamicin and have Hepatotoxicity?

- Check whether Hepatotoxicity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Gentamicin:

Gentamicin (21,654 reports)

Hepatotoxicity treatments and more:

Hepatotoxicity (23,823 reports)

Browse all side effects of Gentamicin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatotoxicity:

Hepatotoxicity (1,081 drugs)

Browse all the conditions that are associated with Hepatotoxicity:

Hepatotoxicity (1,251 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on gentamicin sulfate (the active ingredients of Gentamicin) and Gentamicin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.