Gliclazide and Hypertonia - a phase IV clinical study of FDA data

Summary:

Hypertonia is reported as a side effect among people who take Gliclazide (gliclazide), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Metformin, and have Atrophic vulvovaginitis.

The phase IV clinical study analyzes which people have Hypertonia when taking Gliclazide. It is created by eHealthMe based on reports of 27,903 people who have side effects when taking Gliclazide from the FDA, and is updated regularly.

What is Gliclazide?

Gliclazide has active ingredients of gliclazide. It is often used in diabetes. eHealthMe is studying from 28,131 Gliclazide users. Check the latest studies of Gliclazide.

What is Hypertonia?

Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch) is found to be associated with 491 drugs and 692 conditions by eHealthMe. Check the latest studies of Hypertonia.

On Jul, 09, 2026

27,903 people reported to have side effects when taking Gliclazide.
Among them, 15 people (0.05%) have Hypertonia.

Among these 15 people:

How long have people been on Gliclazide when they have Hypertonia? *

What is the gender of people who have Hypertonia when taking Gliclazide? *

female: 53.85 %
male: 46.15 %

What is the age of people who have Hypertonia when taking Gliclazide? *

What are other drugs people take besides Gliclazide? *

What are other side effects people have besides Hypertonia? *

Nausea And Vomiting: 7 people, 46.67%
Speech Impairment (Adult) (inability to speak (adult)): 6 people, 40.00%
Headache (pain in head): 5 people, 33.33%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 5 people, 33.33%
Defaecation Urgency (a sudden compelling urge to defecate): 5 people, 33.33%
Cerebral Haemorrhage (bleeding within the brain): 5 people, 33.33%
Neck Pain: 5 people, 33.33%
Muscle Twitching: 5 people, 33.33%
Snoring: 5 people, 33.33%
Speech Disorder: 5 people, 33.33%

What are the existing conditions these people have? *

Atrophic Vulvovaginitis (inflammation of the vulva): 5 people, 33.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 26.67%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 4 people, 26.67%
Essential Hypertension (primary hypertension): 4 people, 26.67%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 26.67%
Asthma: 4 people, 26.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 13.33%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 6.67%
Ventricular Tachyarrhythmia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 1 person, 6.67%
Hepatitis B: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Gliclazide and have Hypertonia?

- Check whether Hypertonia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Gliclazide:

Gliclazide (28,131 reports)

Hypertonia treatments and more:

Hypertonia (11,073 reports)

Browse all side effects of Gliclazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypertonia:

Hypertonia (491 drugs)

Browse all the conditions that are associated with Hypertonia:

Hypertonia (692 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on gliclazide (the active ingredients of Gliclazide) and Gliclazide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.