Glimepiride and Polyneuropathy - a phase IV clinical study of FDA data

Summary:

Polyneuropathy is reported as a side effect among people who take Glimepiride (glimepiride), especially for people who are male, 60+ old, also take Aspirin, and have High blood pressure.

The phase IV clinical study analyzes which people have Polyneuropathy when taking Glimepiride. It is created by eHealthMe based on reports of 45,086 people who have side effects when taking Glimepiride from the FDA, and is updated regularly.

What is Glimepiride?

Glimepiride has active ingredients of glimepiride. It is often used in diabetes. eHealthMe is studying from 45,909 Glimepiride users. Check the latest studies of Glimepiride.

What is Polyneuropathy?

Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously) is found to be associated with 914 drugs and 944 conditions by eHealthMe. Check the latest studies of Polyneuropathy.



On Jul, 18, 2026

45,086 people reported to have side effects when taking Glimepiride.
Among them, 24 people (0.05%) have Polyneuropathy.

Could Glimepiride cause Polyneuropathy?

Among these 24 people:

What is the gender of people who have Polyneuropathy when taking Glimepiride? *

  • female: 16.67 %
  • male: 83.33 %

What is the age of people who have Polyneuropathy when taking Glimepiride? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 4.35 %
  • 60+: 95.65 %

What are other drugs people take besides Glimepiride? *

  1. Aspirin: 10 people, 41.67%
  2. Lisinopril: 8 people, 33.33%
  3. Furosemide: 7 people, 29.17%
  4. Synthroid: 7 people, 29.17%
  5. Metformin: 7 people, 29.17%
  6. Zyrtec: 6 people, 25.00%
  7. Nasacort: 6 people, 25.00%
  8. Prilosec: 6 people, 25.00%
  9. Coreg: 6 people, 25.00%
  10. Coumadin: 6 people, 25.00%

What are other side effects people have besides Polyneuropathy? *

  1. Hypoglycemia (low blood sugar): 13 people, 54.17%
  2. Hypotension (abnormally low blood pressure): 7 people, 29.17%
  3. Fall: 7 people, 29.17%
  4. Back Pain: 7 people, 29.17%
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 6 people, 25.00%
  6. Laziness: 6 people, 25.00%
  7. Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 6 people, 25.00%
  8. Drowsiness: 6 people, 25.00%
  9. Pain: 6 people, 25.00%
  10. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 6 people, 25.00%

What are the existing conditions these people have? *

  1. High Blood Pressure: 3 people, 12.50%
  2. Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 2 people, 8.33%
  3. Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries)): 2 people, 8.33%
  4. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 8.33%
  5. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 4.17%
  6. Pain In Extremity: 1 person, 4.17%
  7. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 4.17%
  8. Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 1 person, 4.17%
  9. Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 1 person, 4.17%
  10. Metastases To Liver (cancer spreads to liver): 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Glimepiride and have Polyneuropathy?

- Check whether Polyneuropathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Glimepiride:

Polyneuropathy treatments and more:

How severe was Polyneuropathy and when was it recovered:

Expand to all the drugs that have ingredients of glimepiride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glimepiride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Polyneuropathy:

Browse all the conditions that are associated with Polyneuropathy:


How the study uses the data?

The study uses data from the FDA. It is based on glimepiride (the active ingredients of Glimepiride) and Glimepiride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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