Glipizide and Hypervolaemia - a phase IV clinical study of FDA data

Summary:

Hypervolaemia is reported as a side effect among people who take Glipizide (glipizide), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Lisinopril, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Hypervolaemia when taking Glipizide. It is created by eHealthMe based on reports of 63,661 people who have side effects when taking Glipizide from the FDA, and is updated regularly.

What is Glipizide?

Glipizide has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 64,852 Glipizide users. Check the latest studies of Glipizide.

What is Hypervolaemia?

Hypervolaemia (abnormally increased volume of blood) is found to be associated with 380 drugs and 225 conditions by eHealthMe. Check the latest studies of Hypervolaemia.



On Aug, 04, 2026

63,661 people reported to have side effects when taking Glipizide.
Among them, 18 people (0.03%) have Hypervolaemia.

Could Glipizide cause Hypervolaemia?

Among these 18 people:

How long have people been on Glipizide when they have Hypervolaemia? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypervolaemia when taking Glipizide? *

  • female: 58.82 %
  • male: 41.18 %

What is the age of people who have Hypervolaemia when taking Glipizide? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 21.43 %
  • 60+: 78.57 %

What are other drugs people take besides Glipizide? *

  1. Lisinopril: 10 people, 55.56%
  2. Aspirin: 6 people, 33.33%
  3. Prednisone: 6 people, 33.33%
  4. Vitamin D3: 6 people, 33.33%
  5. Fentanyl: 5 people, 27.78%
  6. Acetaminophen: 5 people, 27.78%
  7. Amlodipine: 5 people, 27.78%
  8. Pantoprazole: 4 people, 22.22%
  9. Lyrica: 4 people, 22.22%
  10. Novolog: 4 people, 22.22%

What are other side effects people have besides Hypervolaemia? *

  1. Acute Kidney Failure: 5 people, 27.78%
  2. Nephrogenic Anaemia (anaemia due to kidney disease): 5 people, 27.78%
  3. Chronic Kidney Disease: 5 people, 27.78%
  4. Cardiac Failure Congestive: 5 people, 27.78%
  5. Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 3 people, 16.67%
  6. Hypotension (abnormally low blood pressure): 2 people, 11.11%
  7. Rectal Haemorrhage (bleeding from anus): 2 people, 11.11%
  8. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 2 people, 11.11%
  9. Fluid Overload (too much fluid in the blood): 2 people, 11.11%
  10. Fall: 2 people, 11.11%

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 33.33%
  2. Indigestion: 4 people, 22.22%
  3. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 16.67%
  4. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 16.67%
  5. Pain: 3 people, 16.67%
  6. Heart Attack: 2 people, 11.11%
  7. Amyloidosis (a tumour within which amyloid is produced): 2 people, 11.11%
  8. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 11.11%
  9. Chronic Kidney Disease: 2 people, 11.11%
  10. Combined Immunodeficiency: 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Glipizide and have Hypervolaemia?

- Check whether Hypervolaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Glipizide:

Hypervolaemia treatments and more:

How severe was Hypervolaemia and when was it recovered:

Expand to all the drugs that have ingredients of glipizide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glipizide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypervolaemia:

Browse all the conditions that are associated with Hypervolaemia:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on glipizide (the active ingredients of Glipizide) and Glipizide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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