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Glumetza and Chronic kidney disease - a phase IV clinical study of FDA data

Summary:

Chronic kidney disease is reported as a side effect among people who take Glumetza (metformin hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Synthroid, and have Pain.

The phase IV clinical study analyzes which people have Chronic kidney disease when taking Glumetza. It is created by eHealthMe based on reports of 1,827 people who have side effects when taking Glumetza from the FDA, and is updated regularly.

What is Glumetza?

Glumetza has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 1,968 Glumetza users. Check the latest studies of Glumetza.

What is Chronic kidney disease?

Chronic kidney disease is found to be associated with 1,825 drugs and 1,365 conditions by eHealthMe. Check the latest studies of Chronic kidney disease.

On Jul, 18, 2026

1,827 people reported to have side effects when taking Glumetza.
Among them, 49 people (2.68%) have Chronic kidney disease.

Could Glumetza cause Chronic kidney disease?

Among these 49 people:

How long have people been on Glumetza when they have Chronic kidney disease? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Chronic kidney disease when taking Glumetza? *

  • female: 38.1 %
  • male: 61.9 %

What is the age of people who have Chronic kidney disease when taking Glumetza? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 12 %
  • 50-59: 32 %
  • 60+: 56 %

What are other drugs people take besides Glumetza? *

  1. Synthroid: 27 people, 55.10%
  2. Metformin: 23 people, 46.94%
  3. Vitamin B12: 21 people, 42.86%
  4. Crestor: 21 people, 42.86%
  5. Nexium: 17 people, 34.69%
  6. Olmetec: 16 people, 32.65%
  7. Benicar: 16 people, 32.65%
  8. Genotropin: 16 people, 32.65%
  9. Magnesium Glycinate: 16 people, 32.65%
  10. Amlodipine: 15 people, 30.61%

What are other side effects people have besides Chronic kidney disease? *

  1. Pain: 21 people, 42.86%
  2. Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 18 people, 36.73%
  3. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 18 people, 36.73%
  4. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 16 people, 32.65%
  5. Weakness: 15 people, 30.61%
  6. Tendonitis (a condition that causes pain and swelling of tendons): 15 people, 30.61%
  7. Bone Disorder: 15 people, 30.61%
  8. Cardiac Disorder: 15 people, 30.61%
  9. Acute Kidney Failure: 14 people, 28.57%
  10. Hypersensitivity: 12 people, 24.49%

What are the existing conditions these people have? *

  1. Pain: 25 people, 51.02%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 20 people, 40.82%
  3. High Blood Pressure: 19 people, 38.78%
  4. Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 17 people, 34.69%
  5. Itching: 16 people, 32.65%
  6. Wound: 15 people, 30.61%
  7. Tendonitis (a condition that causes pain and swelling of tendons): 15 people, 30.61%
  8. Nodule (a growth of abnormal tissue): 15 people, 30.61%
  9. Secondary Adrenocortical Insufficiency (inadequate secretion of acth by the pituitary gland): 15 people, 30.61%
  10. Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 15 people, 30.61%

* Approximation only. Some reports may have incomplete information.

Do you take Glumetza and have Chronic kidney disease?

- Check whether Chronic kidney disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Glumetza:

Chronic kidney disease treatments and more:

How severe was Chronic kidney disease and when was it recovered:

Expand to all the drugs that have ingredients of metformin hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glumetza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chronic kidney disease:

Browse all the conditions that are associated with Chronic kidney disease:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Glumetza) and Glumetza (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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