Glycopyrrolate and Hepatic failure - a phase IV clinical study of FDA data

Summary:

Hepatic failure is reported as a side effect among people who take Glycopyrrolate (glycopyrrolate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Carvedilol, and have Hyperkalemia.

The phase IV clinical study analyzes which people have Hepatic failure when taking Glycopyrrolate. It is created by eHealthMe based on reports of 5,510 people who have side effects when taking Glycopyrrolate from the FDA, and is updated regularly.

What is Glycopyrrolate?

Glycopyrrolate has active ingredients of glycopyrrolate. It is often used in hyperhidrosis. eHealthMe is studying from 5,599 Glycopyrrolate users. Check the latest studies of Glycopyrrolate.

What is Hepatic failure?

Hepatic failure (liver failure) is found to be associated with 1,539 drugs and 1,894 conditions by eHealthMe. Check the latest studies of Hepatic failure.

On Aug, 11, 2026

5,510 people reported to have side effects when taking Glycopyrrolate.
Among them, 15 people (0.27%) have Hepatic failure.

Could Glycopyrrolate cause Hepatic failure?

Among these 15 people:

How long have people been on Glycopyrrolate when they have Hepatic failure? *

What is the gender of people who have Hepatic failure when taking Glycopyrrolate? *

female: 26.67 %
male: 73.33 %

What is the age of people who have Hepatic failure when taking Glycopyrrolate? *

What are other drugs people take besides Glycopyrrolate? *

What are other side effects people have besides Hepatic failure? *

Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 40.00%
Aspartate Aminotransferase Increased: 5 people, 33.33%
Hypokalemia (low potassium): 5 people, 33.33%
Thrombocytopenia (decrease of platelets in blood): 5 people, 33.33%
Abdominal Pain: 4 people, 26.67%
Acute Kidney Failure: 4 people, 26.67%
Hypotension (abnormally low blood pressure): 4 people, 26.67%
Liver Carcinoma Ruptured (ruptured liver cancer tumour): 4 people, 26.67%
Diarrhea: 4 people, 26.67%
Ischaemic Cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease): 4 people, 26.67%

What are the existing conditions these people have? *

Hyperkalemia (damage to or disease of the kidney): 7 people, 46.67%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 40.00%
High Blood Pressure: 5 people, 33.33%
Weakness: 4 people, 26.67%
Hypokalemia (low potassium): 4 people, 26.67%
Aspartate Aminotransferase Increased: 4 people, 26.67%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 4 people, 26.67%
Gastritis (inflammation of stomach): 4 people, 26.67%
Headache (pain in head): 4 people, 26.67%
Hepatic Neoplasm Malignant (liver cancer): 4 people, 26.67%

* Approximation only. Some reports may have incomplete information.

Do you take Glycopyrrolate and have Hepatic failure?

- Check whether Hepatic failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Glycopyrrolate:

Glycopyrrolate (5,599 reports)

Hepatic failure treatments and more:

Hepatic failure (44,058 reports)

Browse all side effects of Glycopyrrolate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic failure:

Hepatic failure (1,539 drugs)

Browse all the conditions that are associated with Hepatic failure:

Hepatic failure (1,894 conditions)

Related publications that referenced our studies

D'souza S, Gowler V, "Glycopyrrolate‐induced respiratory arrest: an unusual side effect", Acta Anaesthesiologica Scandinavica, 2015 Mar .
D'souza S, Gowler V, "Glycopyrrolate‐induced respiratory arrest: an unusual side effect", Acta Anaesthesiologica Scandinavica, 2015 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on glycopyrrolate (the active ingredients of Glycopyrrolate) and Glycopyrrolate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.