Grape seed and Osteoarthritis - a phase IV clinical study of FDA data

Summary:

Osteoarthritis is reported as a side effect among people who take Grape seed (grape), especially for people who are female, 40-49 old, also take Lidoderm, and have Bone neoplasm malignant.

The phase IV clinical study analyzes which people have Osteoarthritis when taking Grape seed. It is created by eHealthMe based on reports of 838 people who have side effects when taking Grape seed from the FDA, and is updated regularly.

What is Grape seed?

Grape seed has active ingredients of grape. eHealthMe is studying from 893 Grape seed users. Check the latest studies of Grape seed.

What is Osteoarthritis?

Osteoarthritis (a joint disease caused by cartilage loss in a joint) is found to be associated with 1,880 drugs and 2,648 conditions by eHealthMe. Check the latest studies of Osteoarthritis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

838 people reported to have side effects when taking Grape seed.
Among them, 22 people (2.63%) have Osteoarthritis.

Among these 22 people:

What is the gender of people who have Osteoarthritis when taking Grape seed? *

female: 90 %
male: 10 %

What is the age of people who have Osteoarthritis when taking Grape seed? *

What are other drugs people take besides Grape seed? *

What are other side effects people have besides Osteoarthritis? *

Joint Pain: 19 people, 86.36%
Pain: 17 people, 77.27%
Pneumonia: 16 people, 72.73%
Weight Increased: 15 people, 68.18%
Primary Sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone): 15 people, 68.18%
Aphthous Stomatitis (mouth ulcer): 15 people, 68.18%
Bone Disorder: 15 people, 68.18%
Decreased Interest: 15 people, 68.18%
Dizziness: 15 people, 68.18%
General Physical Health Deterioration (weak health status): 15 people, 68.18%

What are the existing conditions these people have? *

Bone Neoplasm Malignant (cancer of bone): 14 people, 63.64%
Quit Smoking: 11 people, 50.00%
Breast Cancer: 11 people, 50.00%
Bone Density Decreased: 8 people, 36.36%
Bone Loss: 7 people, 31.82%
High Blood Pressure: 3 people, 13.64%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 13.64%
Seasonal Allergy (allergic condition due to certain season): 2 people, 9.09%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 9.09%
Anaemia (lack of blood): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Grape seed and have Osteoarthritis?

- Check whether Osteoarthritis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Grape seed:

Grape seed (893 reports)

Osteoarthritis treatments and more:

Osteoarthritis (95,655 reports)

Browse all side effects of Grape seed:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteoarthritis:

Osteoarthritis (1,880 drugs)

Browse all the conditions that are associated with Osteoarthritis:

Osteoarthritis (2,648 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on grape (the active ingredients of Grape seed) and Grape seed (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.